ID A0A1Y4UPG3_9FIRM Unreviewed; 215 AA.
AC A0A1Y4UPG3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:OUQ58835.1};
GN Name=cbiC {ECO:0000313|EMBL:OUQ58835.1};
GN ORFNames=B5E58_06545 {ECO:0000313|EMBL:OUQ58835.1};
OS Tyzzerella sp. An114.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Tyzzerella.
OX NCBI_TaxID=1965545 {ECO:0000313|EMBL:OUQ58835.1, ECO:0000313|Proteomes:UP000196526};
RN [1] {ECO:0000313|Proteomes:UP000196526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An114 {ECO:0000313|Proteomes:UP000196526};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUQ58835.1}.
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DR EMBL; NFLT01000005; OUQ58835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4UPG3; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000196526; Unassembled WGS sequence.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000196526}.
FT DOMAIN 12..207
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 215 AA; 23396 MW; 5C211035D09866E4 CRC64;
MLEKIEMISP SDIENRSFQI ISEELGDKKF PPFCENIVKR VIHTTADFDY AENLYISENA
VGKGLKALQS GCTIVTDTTM ALSGINKRVL SSLGGSVKCF IADEDVKEEA KKRGITRSAV
AVEKASKDKN IKIYVVGNAP TALISLYDLI KEGKMEVPDL VVGVPVGFVN VVESKELFVN
SEIPCIIARG RKGGSNVAAA IINALLYIVS ENRRD
//
