ID   A0A1Y4W946_9FIRM        Unreviewed;       535 AA.
AC   A0A1Y4W946;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Stage 0 sporulation protein A homolog {ECO:0000256|ARBA:ARBA00018672};
GN   ORFNames=B5E43_07135 {ECO:0000313|EMBL:OUQ78939.1};
OS   Flavonifractor sp. An100.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Flavonifractor.
OX   NCBI_TaxID=1965538 {ECO:0000313|EMBL:OUQ78939.1, ECO:0000313|Proteomes:UP000196191};
RN   [1] {ECO:0000313|Proteomes:UP000196191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An100 {ECO:0000313|Proteomes:UP000196191};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play the central regulatory role in sporulation. It may
CC       be an element of the effector pathway responsible for the activation of
CC       sporulation genes in response to nutritional stress. Spo0A may act in
CC       concert with spo0H (a sigma factor) to control the expression of some
CC       genes that are critical to the sporulation process.
CC       {ECO:0000256|ARBA:ARBA00024867}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUQ78939.1}.
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DR   EMBL; NFMA01000009; OUQ78939.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4W946; -.
DR   OrthoDB; 9794370at2; -.
DR   Proteomes; UP000196191; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd17536; REC_YesN-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR   InterPro; IPR041522; CdaR_GGDEF.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   PANTHER; PTHR43280; ARAC-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR43280:SF2; BIFUNCTIONAL TRANSCRIPTIONAL ACTIVATOR_DNA REPAIR ENZYME ADAA; 1.
DR   Pfam; PF17853; GGDEF_2; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 2.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:OUQ78939.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196191}.
FT   DOMAIN          5..122
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          433..532
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS01124"
FT   COILED          118..145
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   535 AA;  61143 MW;  FE587740808C444E CRC64;
     MERYRVLLAD DEEEIRVGIS RKIDWESLGF FLVGEAENGA EALELAEQLR PDVVLTDIKM
     PFMDGLELCR RLKQSLPAAK MVVFSGFDDF EYARQAVGMG VSEYIMKPIN APELNGVLTR
     LREQLEQQRM ERRDMEALRR RYEESLPVLR ELFYTRLLDG RLKPDQIQDR AARYELELPE
     GIWTAVLVHV DLPGESEEAE RDELLLLSVR DFFQEHFQME GCAVRSILYN DAVALLVYLK
     QQDQIYPLLE ELERVCALTH SLLGITLTLG VGLPCGGPEE LYASAEGARA ALEYRVLMGG
     EHIIYIGDLE PDHSARLPFE EEDQRELWAA VKLGSVSQVK QVIGGLMDRV REKRLSLSQC
     HLFFLEMVTS LIRLARTGGA EVEDVFGPGF TGVVSINDFR SLDDLEGWLE GCCLKLWEVL
     GRQRSDSAWK TVERAKEFIA VHYADSDLSV ESLCTHLHLS PTYFSTLFKR ETGMSFTAYV
     TEQRMDRAAQ LLRETDEKTY LIAEQTGYTD PNYFSYVFKR HFGVTPSKFR GGRGR
//