ID   A0A1Y4WFZ1_9FIRM        Unreviewed;       625 AA.
AC   A0A1Y4WFZ1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Sigma-54-dependent Fis family transcriptional regulator {ECO:0000313|EMBL:OUQ81350.1};
GN   ORFNames=B5E42_11825 {ECO:0000313|EMBL:OUQ81350.1};
OS   Flavonifractor sp. An10.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Flavonifractor.
OX   NCBI_TaxID=1965537 {ECO:0000313|EMBL:OUQ81350.1, ECO:0000313|Proteomes:UP000196537};
RN   [1] {ECO:0000313|Proteomes:UP000196537}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An10 {ECO:0000313|Proteomes:UP000196537};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUQ81350.1}.
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DR   EMBL; NFMB01000006; OUQ81350.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4WFZ1; -.
DR   OrthoDB; 9803970at2; -.
DR   Proteomes; UP000196537; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.40.50.10660; PrpR receptor domain-like; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR   InterPro; IPR002078; Sigma_54_int.
DR   PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR   PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF06506; PrpR_N; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   PRINTS; PR01590; HTHFIS.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196537};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          197..254
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          330..542
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000259|PROSITE:PS50045"
SQ   SEQUENCE   625 AA;  69468 MW;  2ED1B6250C55D778 CRC64;
     MAKFGLLLPR MEMVEPAGRI ARELGMDVVL NQSTSTEQVL EVAAEARRLG ADILVARGRQ
     ASILRAHTDF PLVEIQLTGL EIARLLHRAR RLAPQGARPR IGVVTIPNMV GSIQGFEDIL
     DIELRTYFVE GNEEMERGAQ QAIADGMDVI LGGDFVNAYC RRLGKRTLFF EGTEDSLRTS
     LLHARSVGLI TDTERRNTAH LQALLDYSFN GILELDPDGV VVRSNDVACK ILELERDKLE
     GQPLASLMPR EDAELWLDAL TQRRELYASV LNVAGVYVVA NAAPVADLDA VEGMVFSFYE
     MQQMERQGER ALRERYRLQR YLAHGRFEDV SHTSREMSRL VKLARSFAET GQPILLWGEV
     GSGKSLFAQS IHNTSPCARG PFVTFDCAAR EADQRALLAQ AGRAADGGTL YLDNLEHLTQ
     GGQRVLCRLL REGVVHLPEE AAPTPSAVRV IASTTGDLAQ LVEEGTFQAE LYYLLIPLRL
     ALPPLRTRPE DLNQAIDMCL DDCVVKFKRY VVLTKEARKR LNDYSWPGNY IQLRAFLERM
     VLTAPSRTVN ASYVMGLLQE LYPVSTARSE GAQAQEMPDS EGARLAEVLS RNGGNRAAAA
     AELGISKTTL WRRMKQYGVK DHYGT
//