ID A0A1Y4WMT1_9FIRM Unreviewed; 422 AA.
AC A0A1Y4WMT1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Integrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5E42_09150 {ECO:0000313|EMBL:OUQ82833.1};
OS Flavonifractor sp. An10.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965537 {ECO:0000313|EMBL:OUQ82833.1, ECO:0000313|Proteomes:UP000196537};
RN [1] {ECO:0000313|Proteomes:UP000196537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An10 {ECO:0000313|Proteomes:UP000196537};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules.
CC {ECO:0000256|ARBA:ARBA00003283}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUQ82833.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NFMB01000004; OUQ82833.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4WMT1; -.
DR OrthoDB; 9785687at2; -.
DR Proteomes; UP000196537; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01188; INT_RitA_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR PANTHER; PTHR30349:SF87; PROPHAGE INTEGRASE INTD-RELATED; 1.
DR Pfam; PF02899; Phage_int_SAM_1; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000196537}.
FT DOMAIN 117..199
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 222..407
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 422 AA; 48482 MW; DAB9A233ACD5E4D2 CRC64;
MVAMGMSVDA AQITVDQMLD IADRELRRLQ LAQGTIYWHC RELRDFADYC VQNAIQIYRP
DTGITYFFQR YGMDMTDPSI KLNEKQRTTR RTIRFLDDIY QFGCARRISR HDYRVPVRYA
SILENYLGYC AKNNGAAGTI DVKRTKLKQF LCYLDGRQVD LPDITASVVS DYMTTLYRYK
RSTIHIISSV LRDFFRYLYM TGVLKDDLSG DVPRPKIYVE ESFPETWTPE EIWQLLSAIN
RRTAVGKRDY AMILLAAVLG MRAGDICALK FREIDWHKKV ITYAQQKSGK INALPLLSPI
GDAIIDYLKN GRLDSDCDNV FIRHVHPYGP IASSSTLSEN IKRYMRQAGM TIRKRKVAHS
MRHTVASTLL KDGVPLMTIS NILGHDTPKT TIAYTKVDIP ALRRCALSYG ERRICRDDGT
IT
//
