ID   A0A1Y5DY22_9PROT        Unreviewed;       302 AA.
AC   A0A1Y5DY22;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN   ORFNames=A9Q83_18450 {ECO:0000313|EMBL:OUR75401.1};
OS   Alphaproteobacteria bacterium 46_93_T64.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria.
OX   NCBI_TaxID=1856292 {ECO:0000313|EMBL:OUR75401.1, ECO:0000313|Proteomes:UP000196525};
RN   [1] {ECO:0000313|Proteomes:UP000196525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hu P., Dubinsky E.A., Probst A.J., Wang J., Sieber C.M.K., Tom L.M.,
RA   Gardinali P., Banfield J.F., Atlas R.M., Andersen G.L.;
RT   "Simulation of Deepwater Horizon oil plume reveals substrate specialization
RT   within a complex community of hydrocarbon-degraders.";
RL   Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUR75401.1}.
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DR   EMBL; MAAN01000041; OUR75401.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y5DY22; -.
DR   Proteomes; UP000196525; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08432; PBP2_GcdR_TrpI_HvrB_AmpR_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30537:SF26; GLYCINE CLEAVAGE SYSTEM TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
FT   DOMAIN          4..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   302 AA;  33790 MW;  81452D976B2AF763 CRC64;
     MRLPPLNSLR AFEVAARLGG FVAASEELNV TPAAISHQVK SLEAHLGVEL FRRLPRGLEL
     TNAGQELMPN ISRGLSHFAR AVGSLSGGDL QGKLTVNVPP SFATLWLVPR MESFIRSFPD
     IRLRVTAYSK APDLIHGETD IRIVYGQGNY PGLKTEYIKE ETIFPVCAPS LLNVSPLRRL
     SDIRNHTLLH DFNIGSDEPS MSWIHWLKRS GVDGSEIRQH VEYSDSVLLT EAAVRGLGVA
     LGRSSLVQDH LNSGKLVRPL KIKKTSEYAY YMLTTEVNAE RPRVRVFLDW LKRQADDDVI
     EW
//