ID   A0A1Y5KDR6_9BACL        Unreviewed;      1066 AA.
AC   A0A1Y5KDR6;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:OUS76781.1};
GN   ORFNames=B1748_09315 {ECO:0000313|EMBL:OUS76781.1};
OS   Paenibacillus sp. MY03.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=302980 {ECO:0000313|EMBL:OUS76781.1, ECO:0000313|Proteomes:UP000195591};
RN   [1] {ECO:0000313|EMBL:OUS76781.1, ECO:0000313|Proteomes:UP000195591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MY03 {ECO:0000313|EMBL:OUS76781.1,
RC   ECO:0000313|Proteomes:UP000195591};
RA   Liu H., Cheng Y., Gu J.Y., Han W.J.;
RT   "Draft genome of a polysaccharide-degrading bacterium Paenibacillus sp.
RT   MY03.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUS76781.1}.
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DR   EMBL; MXQD01000008; OUS76781.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y5KDR6; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000195591; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195591}.
FT   DOMAIN          520..599
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1066 AA;  121692 MW;  7486DEEA0DFC8857 CRC64;
     MLLTVEKLER RVKELSPFRY TNRQEIGQFL FWKDEAAEVA AMPPQDAEWT EVGLGYRWGD
     RDVTAWLRTE VTLPAHQGRN IVGLFNFGKT GPGHTSGFES LLFIDGTPFQ GVGTFHQEVF
     FPEELAGRKI ELLFKVWSGL PGFGPLSELR HILQQAELTL LQQQTDDLYF TASAAMETIK
     VLDSNSWERH ALVKAVDRAF LLVDYRNPGS AAFYESVTAA AVKLHEEIES IPKNNEVTVR
     AIGHTHIDVA WLWRLKHTRE KSARSFSTVL RLMERYPEYA FLQTQPQLYD DLSRDYPVLF
     EQIKKRVKEG RWEAGGAMWL ESDCNIPNGE SLVRQLMYGM RYYEQTFGVS CDYLWLPDVF
     GYSWALPQIL KKSGINYFMT TKISWNVYNR FPHDTFYWRG IDGTEVLTHY ITTPEPGQAA
     DSLTKYYTYN GQVLAETVNG IWKNYRDKEV NDELLLAYGW GDGGGGPTRH MLEMRRRLEH
     MPGLPRVTTG RVDEFFHQLE HTVDKSDRYV HRWNGELYLE LHRGTYTSQG YVKRMNREME
     SLLHTAEAAG VLHGIVSGFK DYPKDTLDES WKIVLRNQFH DILPGSSIAE VYEDCHVEYG
     EAERLAREAL GTSLSGLAGR LPLAPAGEQC WIVVNSLGMA RDELVELAWQ EDFAIGGSWT
     DADGNHLTAE AVVKESGERS VLVRIPNIPA FGYKTISYSS AVESAVSVAE PSIIVKEQGL
     STPFYELTWN SHGQLDRLYD KRTERELIAP GEAANRFDVH EDKPTAHDNW EIDIFYYEKH
     RQINGLQSVV IAENNPLRTV VRMTWNDGET TIKQDMIVYP DNPRIDFVTW VNWQEREQLL
     KVAFPLNVSS TYATHEIQFG NVRRPTHWNT SWDFAQFETC AQRWIDLSER GCGVSLLNNC
     KYGHDVRDNV MRLTLIKSSN DPDPTCDLGE HVFTYSLLPH DGDWFEAGTL EQAARLNTKP
     ETLKLSNLAQ GSAEAIPLTF GLLAIEGGHV VVDTVKRAED SDALIVRCYE YAGMRGNVSL
     RFNASVAEVA EVNLMEREAR EIAHQSNQFA VHFTPYELKT FRVVLS
//