ID A0A1Y5RBL1_9RHOB Unreviewed; 345 AA.
AC A0A1Y5RBL1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN Name=echA8_2 {ECO:0000313|EMBL:SLN13288.1};
GN ORFNames=PAM7066_00174 {ECO:0000313|EMBL:SLN13288.1};
OS Palleronia marisminoris.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Palleronia.
OX NCBI_TaxID=315423 {ECO:0000313|EMBL:SLN13288.1, ECO:0000313|Proteomes:UP000193870};
RN [1] {ECO:0000313|EMBL:SLN13288.1, ECO:0000313|Proteomes:UP000193870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7066 {ECO:0000313|EMBL:SLN13288.1,
RC ECO:0000313|Proteomes:UP000193870};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; FWFV01000001; SLN13288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5RBL1; -.
DR STRING; 315423.SAMN04488020_101172; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000193870; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lyase {ECO:0000313|EMBL:SLN13288.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193870}.
FT DOMAIN 12..332
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 345 AA; 37884 MW; 7E3C11133DBC6F86 CRC64;
MPEIHIRKEG MVGRVTLSRP EALNALTWAM CLEIARALDD WAEDPQVALV ILDAEGTKAF
CAGGDIAEMY RSGIEGDYDY GRSFWRDEYR MNARLAEYPK PIVSFLHGFV MGGGVGLGGH
CSHRIVGESA RIAMPECSIG FVPDVGGTYR LAQAPGRLGE YLGLTAARME PGDALYAGFA
DHFVPEAEWP ALKDALIASG DAGAVAEAAR AAPHGKLVDW QTQIDLFFGG KELADIVRAL
RADGSDFARE TRAALERNAP LSMAVTLKMI RRLRGPSLTI RDALELEYRV SYRIMEHGDF
LEGIRAAIID KDRQPKWRHA SMEVPEADVD HMLAPLARDA LTFRA
//
