ID   A0A1Y5RCK5_9RHOB        Unreviewed;       806 AA.
AC   A0A1Y5RCK5;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=4-methylaminobutanoate oxidase (Formaldehyde-forming) {ECO:0000313|EMBL:SLN13463.1};
DE            EC=1.5.3.19 {ECO:0000313|EMBL:SLN13463.1};
GN   Name=mlr_3 {ECO:0000313|EMBL:SLN13463.1};
GN   ORFNames=PEL8287_00523 {ECO:0000313|EMBL:SLN13463.1};
OS   Roseovarius litorisediminis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=1312363 {ECO:0000313|EMBL:SLN13463.1, ECO:0000313|Proteomes:UP000193827};
RN   [1] {ECO:0000313|EMBL:SLN13463.1, ECO:0000313|Proteomes:UP000193827}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 8287 {ECO:0000313|EMBL:SLN13463.1,
RC   ECO:0000313|Proteomes:UP000193827};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; FWFL01000001; SLN13463.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y5RCK5; -.
DR   OrthoDB; 7156675at2; -.
DR   Proteomes; UP000193827; Unassembled WGS sequence.
DR   GO; GO:0102317; F:4-methylaminobutyrate oxidase (demethylating) activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:SLN13463.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193827}.
FT   DOMAIN          6..364
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          367..420
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          424..689
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          715..798
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   806 AA;  89608 MW;  11FE7E0DC47E2BA6 CRC64;
     MKTTTRVAVI GGGVVGCSVL YHLTKLGWSD VMLIERSELT SGSTWHAAGG FHTLNGDTNM
     AALQGYTIKL YKELEEITGM SCGLHHVGGV TLADNQDRFD MLLAERAKHR YMGLDTHIVT
     PDEIKKIAPI TNTDGILGAL YDPLDGHLDP SGTTHAYAKA ARMGGASIET HCKVIETNQR
     PDGTWDVVTD KGTIHAEHVV NAGGLWAREV GAMAGIYVPL HPMEHQYIVT DDIAEIYERD
     EEHPHVMDPA GESYLRQEGR GLCIGFYEQP CKPWAVDGTP WDFGHELLPD NLDKIEDSIE
     FAYRRFPVLE AAGVKSVIHG PFTFASDGNP LVGPVPGLRN YWSACGVMAG FSQGGGVGLM
     LAQWMIEGEC ERDVTAMDVA RFGDWITPGY TRPKVIENYQ KRFSVAYPNE ELPAARPFRQ
     TPMYDVFDKM GAVWGQQYGL EVVNYFAEED EPRYETPSFR RSNAWEATAR EVRAVRESVG
     INEVHNFGKY LVTGPNARGW LDRIMAGRIP RPGRVSLTPM LSPKGRLIGD FTVSCLGAEA
     FQLTASYGAQ AYHMRWFQMN EAEDVAVENI SDRLNGFQIA GPWAREVLVA CTRDKVGDMK
     FMDLRHATIG MVDCLIQRVS YTGDLGYEIY CDPMSQRALW DVLMREGHAY DIQPFGMRAM
     MSLRLDRFFG SWLSEFSPDY TPGETRMDRF IRFDKTTDFI GRAAASAERE SGSERKLVAF
     EVDALDADAH GYEPIWIDGK VQGFCTSGGY SHHAKKSIAL GLIPRDLAEA AEYSTLTAKI
     EILGQMRPAT LISDPLLDPE GDHMRS
//