ID A0A1Y5SEI4_9RHOB Unreviewed; 456 AA.
AC A0A1Y5SEI4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=UDP-N-acetyl-D-glucosamine 6-dehydrogenase {ECO:0000313|EMBL:SLN38157.1};
DE EC=1.1.1.136 {ECO:0000313|EMBL:SLN38157.1};
GN Name=wbpA {ECO:0000313|EMBL:SLN38157.1};
GN ORFNames=PEL8287_01855 {ECO:0000313|EMBL:SLN38157.1};
OS Roseovarius litorisediminis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1312363 {ECO:0000313|EMBL:SLN38157.1, ECO:0000313|Proteomes:UP000193827};
RN [1] {ECO:0000313|EMBL:SLN38157.1, ECO:0000313|Proteomes:UP000193827}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8287 {ECO:0000313|EMBL:SLN38157.1,
RC ECO:0000313|Proteomes:UP000193827};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; FWFL01000004; SLN38157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5SEI4; -.
DR Proteomes; UP000193827; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0047004; F:UDP-N-acetylglucosamine 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:SLN38157.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193827}.
FT DOMAIN 347..444
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 456 AA; 49749 MW; 1C29A0007B0A77E1 CRC64;
MNVILNTALS DLTHVSEVER SIRLVLDNTP TKATFENIAV VGLGYVGLPL AVCLSEKFKK
VAGFDISDRR VGEIQRGHDA TNEINEFALK RSGLRVSNNL AEIAEASFYI VTVPTPINDA
RQPDLSPLRS ACEMIGPNLD KGDVVVFEST VYPGVTEDFC APILEEFSGL KAGRDFGLGY
SPERINPGDK INTVENVVKV VSGDTPDTLN RVIAVYDLVI EAGVHAAPNI KVAEAAKVLE
NTQRDVNIAL MNEMSLICDK IGISTNEVIE AAATKWNFLP FTPGLVGGHC IGVDPYYLAS
LAEKVGHNPQ VIMAGRRTND GMVRHIADAA LRLMIEKGSA VRDLRVGVCG ITFKENVPDV
RNSKALELIE ALRGYGIDPL VHDPHCSPDI VRPLGVKLCS AEDMSDLDVM ILATPHEKFI
YDSRFLDKIR DDGILVDVRG AFRNSKKARA LTYWSL
//
