ID   A0A1Y5T6B1_9RHOB        Unreviewed;       824 AA.
AC   A0A1Y5T6B1;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=4-methylaminobutanoate oxidase (Formaldehyde-forming) {ECO:0000313|EMBL:SLN54743.1};
DE            EC=1.5.3.19 {ECO:0000313|EMBL:SLN54743.1};
GN   Name=mlr_14 {ECO:0000313|EMBL:SLN54743.1};
GN   ORFNames=TRL7639_02907 {ECO:0000313|EMBL:SLN54743.1};
OS   Falsiruegeria litorea R37.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Falsiruegeria.
OX   NCBI_TaxID=1200284 {ECO:0000313|EMBL:SLN54743.1, ECO:0000313|Proteomes:UP000193077};
RN   [1] {ECO:0000313|EMBL:SLN54743.1, ECO:0000313|Proteomes:UP000193077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7639 {ECO:0000313|EMBL:SLN54743.1,
RC   ECO:0000313|Proteomes:UP000193077};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; FWFO01000002; SLN54743.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y5T6B1; -.
DR   OrthoDB; 7156675at2; -.
DR   Proteomes; UP000193077; Unassembled WGS sequence.
DR   GO; GO:0102317; F:4-methylaminobutyrate oxidase (demethylating) activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:SLN54743.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193077}.
FT   DOMAIN          28..386
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          389..442
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          445..713
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          738..816
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   824 AA;  91148 MW;  57060B3DA9D57080 CRC64;
     MSDQFTQSTL NIHKEEGTGG KPLPSHAKVV VIGGGVVGCS ILFHLAKFGW KDVVLLERDE
     LTSGSSWHAA GQIHTISSDP NISRLQSYTI DLYKEIEETS GHSVGLHITG GFYLASNKTW
     YDYLKRERSK ARYMGLNQEF ISPAEVAERH PLIDPKHYYA ALWDDQDGDL DPSGATYAFA
     KSAKVHGAQY FTHCGVTATR QRPDGSWDVT TPKGVINAEH IVNCGGLWAR EVGHMQGLNL
     PVQPMEHHYL ITEKIDAVAK HPTRLPAGID YEANIYFRQE RQGMLLGTYE PKGTPWKVGG
     TPWDFGHELL QPDLDRIADR LEMSFERIPA IGEVGIKDMI NGPFTFGPDG NPMIGPVPGM
     KNYWCAVGVM AGFCQGGGVG LTMAEWMIDG EPSIDVWAMD VARFGDFATP DWGTVKSTEN
     YERRFVMTFP NETLPKGRMQ KTTALYDRLV ARGARMGQGF GLENALWFAD GPEDAHEEPT
     FERNRSHEYV AREVQAVREA VGGIEIANFA KHEFKGPGAR SYLDRVLAGY VPKPGRLTLT
     PMLTPNGKLY GDLTVACLGE EHFMLFGSGA MQEAHRRWFE KDLPDDVSYA NVSDDWHGIA
     LSGPKSRALL QGIMREDISA QTFKFRDLRQ TFVGGVPVIL NRISFSGELG YEIYCKPQYL
     LRLAEAIEEA GADLGYRWYG ARALMSMRLE KGWGVWTLDF RPDFDAVESG MDVFINWKKD
     FVGKDATLAA RAAGPKQRLV TMTIDVDGID VSNDEAILKD GAAVGYVSSG GYAHHAQRSM
     AMGYIAAEHA APGTQLQVEI LGEMYDTEVL GAPIYDANGA NMRA
//