ID A0A1Y5TG30_9PROT Unreviewed; 549 AA.
AC A0A1Y5TG30;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Rhamnosyl O-methyltransferase {ECO:0000256|ARBA:ARBA00016626};
GN ORFNames=OCH7691_02824 {ECO:0000313|EMBL:SLN63184.1};
OS Oceanibacterium hippocampi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sneathiellales;
OC Sneathiellaceae; Oceanibacterium.
OX NCBI_TaxID=745714 {ECO:0000313|EMBL:SLN63184.1, ECO:0000313|Proteomes:UP000193200};
RN [1] {ECO:0000313|EMBL:SLN63184.1, ECO:0000313|Proteomes:UP000193200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7691 {ECO:0000313|EMBL:SLN63184.1,
RC ECO:0000313|Proteomes:UP000193200};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the O-methylation of the hydroxyl group located on
CC C-2 of the first rhamnosyl residue linked to the phenolic group of
CC glycosylated phenolphthiocerol dimycocerosates (PGL) and p-
CC hydroxybenzoic acid derivatives (p-HBAD).
CC {ECO:0000256|ARBA:ARBA00003116}.
CC -!- SIMILARITY: Belongs to the rhamnosyl O-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00007565}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FWFR01000002; SLN63184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5TG30; -.
DR InParanoid; A0A1Y5TG30; -.
DR OrthoDB; 189417at2; -.
DR Proteomes; UP000193200; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd08946; SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR007072; RNMT_CmcI.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR40048; RHAMNOSYL O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR40048:SF1; RHAMNOSYL O-METHYLTRANSFERASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR Pfam; PF04989; RMNT_CmcI; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SLN63184.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193200};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000313|EMBL:SLN63184.1}.
FT DOMAIN 5..212
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 549 AA; 60533 MW; DAFA2577C46561B5 CRC64;
MKFTIFGAGG FIGRRLSDTL KASGHEVATP DRTWLSGARN SDFKVAPYNA DLGQVIYCIG
MTADFREKKR ETVDAHVSLL NTILHSTKFE SFLYLSTTRV YLGCETTSEA ARLSVDPQAA
DDLYNLSKIM GESACLSLDN PKIRVARVSN VAGFDPNSQN FLNSVIRTAV TSDALTLGES
LESAKNYVYV DDVVEALINI ATRAKGRIYN VAGPDNVSHG DIAAALGRLT GVKTTVADKA
PTRIFPPIDM GRYSAEFPPI TRSLNDVIDD VVNSYRGYHH ALDPASRGET TIDEARGIVR
YRDEARGIAL ELPMESAEGW EVASKAWLRV GWDVKHIYTF TWMGRPIIQL PEDMIRIQEL
IHTTRPDVII ETGIAHGGSL IYYASLFEAM GHGRVIGVDI QIRPHNRRAI EEHPLFKRIE
MFEGSSTSQA IVDQVKARIG KDDKVMLILD SNHTKDHVLA ELRAYAPLVT VGCYAVAADG
IMAQVAGGPR TGADWPVSNP TEAARAYVAE NEDFVIDMPA FEFNESPLRH HVTYWPDGYL
RRVKDSAAG
//
