ID A0A1Y5TQV0_9RHOB Unreviewed; 308 AA.
AC A0A1Y5TQV0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Pyrroline-5-carboxylate reductase {ECO:0000313|EMBL:SLN69916.1};
DE EC=1.5.1.2 {ECO:0000313|EMBL:SLN69916.1};
GN Name=proC_3 {ECO:0000313|EMBL:SLN69916.1};
GN ORFNames=ROA7023_03398 {ECO:0000313|EMBL:SLN69916.1};
OS Roseisalinus antarcticus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseisalinus.
OX NCBI_TaxID=254357 {ECO:0000313|EMBL:SLN69916.1, ECO:0000313|Proteomes:UP000193900};
RN [1] {ECO:0000313|EMBL:SLN69916.1, ECO:0000313|Proteomes:UP000193900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7023 {ECO:0000313|EMBL:SLN69916.1,
RC ECO:0000313|Proteomes:UP000193900};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FWFZ01000022; SLN69916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5TQV0; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000193900; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:SLN69916.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193900};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..297
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 308 AA; 33160 MW; CEE59904CCF5EE30 CRC64;
MAQAPIYERV ALIGLGLIAS SMFWAMKRGG LAGEVRGFAR SAETRAAARE IGLCDVVCDT
AVEAVADADL VVLCVPVGVM AAVAAEIAPV LKPGATVSDV GSVKRAVIES VGPNIPPGVN
FVPAHPLAGT EQSGPRSGFA ELFDNRWCLL VPVENSDPEA VSRLEALWRG MGSNVERMDA
DHHDLVLAVT SHTPHLIAYT MVGVADDLQR VTDSEVVKYS AAGFRDFTRI AASDPTMWRD
VFLTNKEATL EILGRFTEEL FALQRAIRLG DGEHLFEYFT RTRAVRRGIV EAGQDTDAPD
FGRTGKPR
//
