ID A0A1Y5TZJ1_9PROT Unreviewed; 396 AA.
AC A0A1Y5TZJ1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Multidrug resistance protein MdtE {ECO:0000313|EMBL:SLN76766.1};
GN Name=mdtE {ECO:0000313|EMBL:SLN76766.1};
GN ORFNames=OCH7691_04186 {ECO:0000313|EMBL:SLN76766.1};
OS Oceanibacterium hippocampi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sneathiellales;
OC Sneathiellaceae; Oceanibacterium.
OX NCBI_TaxID=745714 {ECO:0000313|EMBL:SLN76766.1, ECO:0000313|Proteomes:UP000193200};
RN [1] {ECO:0000313|EMBL:SLN76766.1, ECO:0000313|Proteomes:UP000193200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7691 {ECO:0000313|EMBL:SLN76766.1,
RC ECO:0000313|Proteomes:UP000193200};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FWFR01000005; SLN76766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5TZJ1; -.
DR InParanoid; A0A1Y5TZJ1; -.
DR OrthoDB; 9816569at2; -.
DR Proteomes; UP000193200; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF10; HLYD FAMILY SECRETION PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000193200}.
FT DOMAIN 71..300
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 110..137
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 396 AA; 43170 MW; 03E7157AB2F5DA76 CRC64;
MQTLITTPAS GRRERNSRVT PLGVALFAML IGIQPAGAQQ QAPAVTVATP LARELVEYDD
FTGQFAAVES VEIRSRVSGY LQSINFQDGQ IVRKGDLLFQ IDPRPFEAEL ASAKARLAQA
EAQVELANQQ LKRAEQLRKN DFVSRSAYDE RMAELRVASG AAEIARAEIR SVALDVEFAR
ILSPIDGRIS RHEVSVGNLV TGGAAGTPTL LTTIVSIDPI HFVFDMSETD FLAYQRAVAK
GLLKSQRDAV EVYARLADEP DWPRVGTLDY IDNRVDRTSG TIRVRAVFPN PDGFLTPGQF
GRIRIPGSEP YTALLIPESA VLSDQSQKIV MVLGENNVVQ ARIVRLGPTY DGLRIVRAGL
EPDDRIVIAG LMRIRAGATV TPEEGVIEGI GEKRPG
//
