ID A0A1Y5U0I8_9PROT Unreviewed; 390 AA.
AC A0A1Y5U0I8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Putative efflux pump periplasmic linker TtgA {ECO:0000313|EMBL:SLN75606.1};
GN Name=ttgA {ECO:0000313|EMBL:SLN75606.1};
GN ORFNames=OCH7691_03900 {ECO:0000313|EMBL:SLN75606.1};
OS Oceanibacterium hippocampi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sneathiellales;
OC Sneathiellaceae; Oceanibacterium.
OX NCBI_TaxID=745714 {ECO:0000313|EMBL:SLN75606.1, ECO:0000313|Proteomes:UP000193200};
RN [1] {ECO:0000313|EMBL:SLN75606.1, ECO:0000313|Proteomes:UP000193200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7691 {ECO:0000313|EMBL:SLN75606.1,
RC ECO:0000313|Proteomes:UP000193200};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FWFR01000004; SLN75606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y5U0I8; -.
DR InParanoid; A0A1Y5U0I8; -.
DR OrthoDB; 7811737at2; -.
DR Proteomes; UP000193200; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000193200};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..390
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012554399"
FT DOMAIN 40..358
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 63..291
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 368..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 105..132
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 390 AA; 41812 MW; E9BDAA850AE35717 CRC64;
MSYLGIKFRR VVLAGAMLLM AMPVAFAQSA APGERPPQAV TVVTLAEQDI TLTATLPGRI
VASALAEVRP QVNGIIIRRT FEEGANVALG DPMYRIDPDS YEARVAAARA QVAQAEAKYT
ASRKEAERAA ELIGRGVSTE QRLENAAAVR DADAAALKVA KADLQSAEID LKRTTIRAPL
AGVVGRSLTT QGALVTAGQA TPLAVIRTLD PVHVDVTQSA AELLEWRRGR TREKLGDGST
EVTLILADGE VFPHTGEMTA AEPHVDELTG VVTLRMEFAN PEHLLLPGMY VQVKMPQRVL
KNVVLAPQQG VSRDRRGRPI AFVANADDVV EQRELTIAQA QGSHWVITDG LKAGDRLIIE
GLQKIGPQMK VAPEERKPPE TTATTAPSSN
//
