ID   A0A1Y6BJP4_9PROT        Unreviewed;       742 AA.
AC   A0A1Y6BJP4;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:SMF14578.1};
GN   ORFNames=SAMN05428998_105278 {ECO:0000313|EMBL:SMF14578.1};
OS   Tistlia consotensis USBA 355.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Fodinicurvataceae; Tistlia.
OX   NCBI_TaxID=560819 {ECO:0000313|EMBL:SMF14578.1, ECO:0000313|Proteomes:UP000192917};
RN   [1] {ECO:0000313|EMBL:SMF14578.1, ECO:0000313|Proteomes:UP000192917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USBA 355 {ECO:0000313|EMBL:SMF14578.1,
RC   ECO:0000313|Proteomes:UP000192917};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWZX01000005; SMF14578.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y6BJP4; -.
DR   STRING; 560819.SAMN05428998_105278; -.
DR   Proteomes; UP000192917; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192917};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        360..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        417..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          478..616
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   742 AA;  79573 MW;  4DCAC134AA6B4488 CRC64;
     MRRRRWPVLA SGLIALAAMV CLRVLDPAPI QALRLRAFDL YQRTEPRPYR PVPVTVLDID
     EAALAAEGQW PWPRSTVALM VERLRALDAA AIAFDILFSE PDRTSPRQLL RDLPDTPEGA
     ALAERLRALP DHDEQLAAAM ASAPTVAAVA LFHGAEGNPE SPPQKAGFAF AGSDPAGFLP
     RYRGALRDLP PIERAASGLG SITFDPDFDG VVRRLPLLQV LGTAILPSLS VEALRVAQGA
     STLIARSADA SGALGLAESG GLSAIKVGRF VVPTTAEGAL WLWYHGPLEG RRLSAAGLLG
     DGWADLRPAV EGRILLVGTS AQGLRDQRAT PLSGSVAGVE IHAEALEQML AGTFLTRPDW
     AEGAEIVALV LLGLLFVLLL PLAGALWCAL LGVLAVGAGL AASWLAFSRA HFLLDPVYPA
     LAAFVVYLTV TTLRYALSER ERDRVRGAFS RYLAPALVER LAERPQALKL GGESREITVL
     FADIRGFTTL SERLTPEELT ACLNRFLTPM TDALLAEGAT IDKYIGDAIM AFWNAPLDQP
     DHPRRALRGA LAMRRRLAEL APRWAEEDAA AGREPIEIRI GIGLNSGPCV VGNLGSEQRF
     DYSALGDTVN LTSRLEGMSK VYRVDILVGE DTALQAAGFA LVELDRVRVV GRAHPVAVFA
     ALGDESLAAD PDFQALKARH EAALAAYRAG AWDEAEAAFG ALRDTTDPLL RSVCPVFLER
     IAAFRGAPPA ADWDGVFRAE HK
//