GenomeNet

Database: UniProt
Entry: A0A1Y6C0C4_9ALTE
LinkDB: A0A1Y6C0C4_9ALTE
Original site: A0A1Y6C0C4_9ALTE 
ID   A0A1Y6C0C4_9ALTE        Unreviewed;       355 AA.
AC   A0A1Y6C0C4;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   08-MAY-2019, entry version 6.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN02745866_02492 {ECO:0000313|EMBL:SMF38959.1};
OS   Alteromonadaceae bacterium Bs31.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae.
OX   NCBI_TaxID=1304903 {ECO:0000313|EMBL:SMF38959.1, ECO:0000313|Proteomes:UP000192901};
RN   [1] {ECO:0000313|EMBL:SMF38959.1, ECO:0000313|Proteomes:UP000192901}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bs31 {ECO:0000313|EMBL:SMF38959.1,
RC   ECO:0000313|Proteomes:UP000192901};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FXAI01000006; SMF38959.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000192901; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000192901};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192901};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       43    339       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   355 AA;  38383 MW;  E00952B8B415A341 CRC64;
     MSNIQDLNVV SQDVLVTPNE LQQELPLSEN AAATVNLGRE TVRNILDRKD PRLIVVVGPC
     SIHDPEAAMD YAKKLKQLSD KVKDTLYIVM RVYFEKPRTT TGWKGLINDP HMNDSFKIEE
     GLRVGRKLLL DIAELGLPAS TEALDPISPQ YLQDLISWSA IGARTTESQT HREMASGLSS
     AVGFKNGTDG GLTVAINALQ SVSSPHRFLG INKDGSVSVI TTRGNAYGHV VLRGGSDKPN
     YDSVSVAMCE KVLTGAKISS NIMIDCSHAN SNKNHELQPL VMDNVCNQIL EGNQSIIGVM
     IESNIGAGNQ KIPADLSQLQ YGVSVTDACV DWATTEEMLT NAADKLSQAL PSRIG
//
DBGET integrated database retrieval system