ID A0A1Y6EE53_9SPHN Unreviewed; 312 AA.
AC A0A1Y6EE53;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SMQ59451.1};
GN ORFNames=SAMN06297468_0286 {ECO:0000313|EMBL:SMQ59451.1};
OS Altererythrobacter xiamenensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Altererythrobacter.
OX NCBI_TaxID=1316679 {ECO:0000313|EMBL:SMQ59451.1, ECO:0000313|Proteomes:UP000194420};
RN [1] {ECO:0000313|Proteomes:UP000194420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FXWG01000001; SMQ59451.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y6EE53; -.
DR OrthoDB; 9787219at2; -.
DR Proteomes; UP000194420; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000194420}.
FT DOMAIN 22..302
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 105..274
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 312 AA; 34387 MW; D328410DE3360F29 CRC64;
MTTLALSALI RPMVEPRLPD GLDVHWFASR EEALEVAPLA EIGWFDFNEK EPMIETLRAA
TKLKWLNSIY AGLDFLPMDV LIERGITVTN GAGINAITIA EYVVMGMLNI AKGYREVVRA
QDRHEWLMDS PGKRELAGSK ALLLGYGAIG KLIKPRLEAF DVDVTVVRRS GGEGVLTPDE
WRGKLGEFDW VILAVPATPE TDGMIGASEL AAMKSDAVLV NIARGAVIDQ PALVEALEAK
SIGSAFLDVT TPEPLPEDHR LWSLENAHIT MHLSGRAQDK MFKRSADRFL ENLDHYLKGE
PVSPVFDPKL GY
//
