ID A0A1Y6EST9_9GAMM Unreviewed; 293 AA.
AC A0A1Y6EST9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=6-carboxy-5,6,7,8-tetrahydropterin synthase {ECO:0000256|ARBA:ARBA00018141};
DE EC=4.1.2.50 {ECO:0000256|ARBA:ARBA00012982};
DE AltName: Full=Queuosine biosynthesis protein QueD {ECO:0000256|ARBA:ARBA00031449};
GN ORFNames=SAMN06297229_1355 {ECO:0000313|EMBL:SMQ65784.1};
OS Pseudidiomarina planktonica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Idiomarinaceae; Pseudidiomarina.
OX NCBI_TaxID=1323738 {ECO:0000313|EMBL:SMQ65784.1, ECO:0000313|Proteomes:UP000194450};
RN [1] {ECO:0000313|Proteomes:UP000194450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=7,8-dihydroneopterin 3'-triphosphate + H2O = 6-
CC carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) +
CC triphosphate; Xref=Rhea:RHEA:27966, ChEBI:CHEBI:15343,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18036,
CC ChEBI:CHEBI:58462, ChEBI:CHEBI:61032; EC=4.1.2.50;
CC Evidence={ECO:0000256|ARBA:ARBA00001293};
CC -!- PATHWAY: Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005061}.
CC -!- SIMILARITY: Belongs to the PTPS family. QueD subfamily.
CC {ECO:0000256|ARBA:ARBA00008900}.
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DR EMBL; FXWH01000001; SMQ65784.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y6EST9; -.
DR OrthoDB; 5820615at2; -.
DR UniPathway; UPA00391; -.
DR Proteomes; UP000194450; Unassembled WGS sequence.
DR GO; GO:0070497; F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.479.10; 6-pyruvoyl tetrahydropterin synthase/QueD; 2.
DR InterPro; IPR007115; 6-PTP_synth/QueD.
DR InterPro; IPR038418; 6-PTP_synth/QueD_sf.
DR Pfam; PF01242; PTPS; 2.
DR SUPFAM; SSF55620; Tetrahydrobiopterin biosynthesis enzymes-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000194450}.
SQ SEQUENCE 293 AA; 33069 MW; BE01E1886F00E3B8 CRC64;
MQLFVNDLTV IDFSYLCPQR GIVGESWIVD IILDGALNEQ SMVLDFGRVK KQIKAIIDDS
VDHKLAVPAE HEYTQVTRNE DKSSYWVDFM RPNERSIHLH CPADAFAFID SEQVTIDTVT
DYLRAVIKRE LPENVAGLQL QLRAEAIPGA FYHYTHGLKK HDGNCQRIAH GHRSRLYISL
DGKRSETLEA AWCERWRDIY IGSLEDEVSL AEVDCSQTAG QCNEHTHVAY AYTADQGLFE
LLVPRGENYI IPTDSTVECL AQYLADQVKQ QYPQAKVQVT AFEGVGKGAI GYA
//
