ID   A0A1Y6IT54_9VIBR        Unreviewed;      1049 AA.
AC   A0A1Y6IT54;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Multidrug resistance protein MdtB {ECO:0000313|EMBL:SMS00808.1};
GN   Name=mdtB {ECO:0000313|EMBL:SMS00808.1};
GN   ORFNames=VIM7927_02079 {ECO:0000313|EMBL:SMS00808.1};
OS   Vibrio mangrovi.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=474394 {ECO:0000313|EMBL:SMS00808.1, ECO:0000313|Proteomes:UP000196125};
RN   [1] {ECO:0000313|EMBL:SMS00808.1, ECO:0000313|Proteomes:UP000196125}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7927 {ECO:0000313|EMBL:SMS00808.1,
RC   ECO:0000313|Proteomes:UP000196125};
RA   Song R., Chenine A.L., Ruprecht R.M.;
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FXXI01000003; SMS00808.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y6IT54; -.
DR   OrthoDB; 9758297at2; -.
DR   Proteomes; UP000196125; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF16; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        348..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        448..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        475..499
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        894..912
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        919..939
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        945..969
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        989..1009
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1021..1043
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1049 AA;  115012 MW;  86CDB0F363957605 CRC64;
     MERKLGISGR IAAMFQHSAI TPLLALVGLL MGVFAVMVTP KEEEPQIDVT FADIFIPFPG
     ASPAEVEHLV TNPAEQIVSE IQGIDNIYSF SQPDGALIVA IFKVGVSRND AVVRTYNKLY
     SNKDWMPAGV GVGEPVIKPR GIEDVPIVSL TLSDPGNHMS QQQLTEVAHG LETELKRIDG
     TRDIYTVGGH DMIVDVRLDP ARMNSFGITI DQLNQVFQSA NVRSPQLTVT QDNQAIPVRV
     GQFLHRVDDV RQLVVGLHNA APVYLSDIAS VSMGGDTPAH NVWTSDKSTI TPAVTIAIAK
     KAGENAVDVA QSVEARLQVL ENQLIPADVK VDVTRNYGNT ASEKSHTLIG KLMFATCAVV
     ILVLLTMGWR EAIVVGIAVM ITLMITLFAS WAWGFTINRV SLFALIFSIG ILVDDAIVVV
     ENIHRHMSSK SDNFSVPYAV DEVGGPTILA TFTVIAALLP MAFVTGLMGP YMSPIPINAS
     MGMFISLAVA FILTPWLAVK LLRHKSHTQE KEPSMAIVQR IMAPFVLSAH QRRNRWLLGG
     GVIVLILGSV LLPVYQAVVL KMLPFDNKSE FQVILDMPDD TALERTQRVL FELGTVLNQS
     PEVHDYQIYA GTAAPMNFNG LVRHYFTRSS PYQGDIQVNL LPKGERDKDS HQIAGELRPK
     LVEVAKAFGG KVKVVEVPPG PPVWSPILAE VYGPTDTVRT EAARQIRQLF EASADIVDVD
     IYLPEPHQQW QVKIDRSKAA HYQVSYASIV NTLAAAVGGQ PVSYLHTDYS KYPVPIQIQA
     TEGDKANLTQ LLEMRVAGQS GQSYPLSDLV SIHKVAADDY IMHKNLVPMV MVVGDMSGHT
     DSPLYGMFEI ATRMKTLPFP VEQNYIHQPS GLSQISVLWD GEWKITYETF RDMGIAYAVG
     MILIYLLVVA HFKSYLTPLI IMAPIPLTII GVMPGHALLQ AQFTATSMIG MIALAGIIVR
     NSILLVDFIR QEHEQGMAFS EAVINSVKVR AKPILLTALA AMIGSLFILD DPIFNGLAIS
     LIFGVFVSTL LTLIVIPVLY FSFMKERRL
//