ID A0A1Y6KXI1_9GAMM Unreviewed; 504 AA.
AC A0A1Y6KXI1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Multidrug resistance protein NorM {ECO:0000256|ARBA:ARBA00013489};
DE AltName: Full=Na(+)/drug antiporter {ECO:0000256|ARBA:ARBA00030855};
GN Name=mepA_4 {ECO:0000313|EMBL:SMY16784.1};
GN ORFNames=PAQU9191_02024 {ECO:0000313|EMBL:SMY16784.1};
OS Photobacterium aquimaris.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=512643 {ECO:0000313|EMBL:SMY16784.1, ECO:0000313|Proteomes:UP000196485};
RN [1] {ECO:0000313|Proteomes:UP000196485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=type strain: CECT 9192 {ECO:0000313|Proteomes:UP000196485};
RA Rodrigo-Torres L., Arahal R. D., Lucena T.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FYAH01000003; SMY16784.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y6KXI1; -.
DR Proteomes; UP000196485; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43823:SF3; MULTIDRUG EXPORT PROTEIN MEPA; 1.
DR PANTHER; PTHR43823; SPORULATION PROTEIN YKVU; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000196485};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 504 AA; 52905 MW; A718114A431874AE CRC64;
MNKKNTTDNN QAKFLTGSTM RHIIVMSGTG AIGLMALFLV DLLDMFFISM LGQIELAAAI
GFAGTLVFFS TSISIGTSIA AGALVSRALG KNDRQLARMM ASNVMIFAVL ISAIVVGLML
WQLPLLLNLI GAKGAVAKAA TQYLVILLPS APLIAVSMSA GAALRGVGDA RSSMVATLIG
GGVNAVLDPL FIFGLSMGMQ GAAIASVFAR LAVMCFSLYA VVYKHRLVAK PDLSSFKLAL
PTVAKIALPA ILTNTATPIG NAVVTSNIAQ FGESFVAGYA VIGRIMPVCF ALVFSLSGAV
GPIIGQNFGG ERWDRINQIL RDAMLFTAVY CVTVSIILWF GQDLLIAMFS LTGDAAEIVG
VFCSFIAITF IFNGALFVAN AAFNNLNRPT WSTVLNMGKA TLGTIPFVLI GGHIAGASGV
LIGQAVGSVV FGIIGFSLVI YQVKKMGLAH EQQPLQSNEI LTPSVPVAPF CSSRTYMGTE
DVLEETLATE MEPSNNITSS KKSD
//
