ID   A0A1Y6L0C3_9GAMM        Unreviewed;       693 AA.
AC   A0A1Y6L0C3;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   Name=helD_3 {ECO:0000313|EMBL:SMY16767.1};
GN   ORFNames=PAQU9191_02007 {ECO:0000313|EMBL:SMY16767.1};
OS   Photobacterium aquimaris.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=512643 {ECO:0000313|EMBL:SMY16767.1, ECO:0000313|Proteomes:UP000196485};
RN   [1] {ECO:0000313|Proteomes:UP000196485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=type strain: CECT 9192 {ECO:0000313|Proteomes:UP000196485};
RA   Rodrigo-Torres L., Arahal R. D., Lucena T.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|ARBA:ARBA00009922}.
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DR   EMBL; FYAH01000003; SMY16767.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y6L0C3; -.
DR   Proteomes; UP000196485; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   CDD; cd17932; DEXQc_UvrD; 1.
DR   CDD; cd18807; SF1_C_UvrD; 1.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR022161; Helicase_IV_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12462; Helicase_IV_N; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000196485}.
FT   DOMAIN          195..511
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         216..223
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   693 AA;  79691 MW;  2D8B4511E23A1B26 CRC64;
     MQLSASRLAQ WLVQGDYYSI ALDGNSLVLD SQTTSDVISF DDWDGSVEIH RGVLWGALEL
     TSSNQQYCWT VHGLPWHECK SFAAFLVRSY QDWAQNRVDK LDAMLPEMLQ RIAFFSNKSG
     YLRHSEHHEL HQFLNDVLQD SDLSPELAAT FRPRSFEKIS PWLGEHQAWV EEHNQQWLVQ
     QSQKWGSWFD SFEKSPLNES QRRAALINQD YNLVLAGAGT GKTSVLVARA GYLIASQAAV
     PEDILMLSFG RKAAEEMTDR LKQKVSDRVK VATFHSLGSQ IIRDVEHDKP NVASITLDVR
     ARSAWVARML IEQWNNSTAA SQWQRHLTQW RVPGFSKENS MEQQAENEQL QAWVWRHIEL
     LGQSGMKKEA LLEAIVNNNN PAMRPRMKSE LTLLWPCYQA YLQHLKVKKQ IDFNSMIEVA
     TEYVKTGKFV SPWRYIMVDE YQDISPQRLA LVEALCHQKV TGHTTPTLFA VGDDWQAIYH
     FAGADVNLTT DFEGRFGNSN ISELSTTYRF NSMIGEVANV FIQQNPSQIK KQLTSFTKQS
     KKAVTLLATD LLPQELIRLS KHYENKTTTV LILGRNNKQK PEKFETWKTQ WPQLNLEYMT
     CHSSKGREAD YVFIVDVNKG IFPSPDRETG LAAIMQSRTE TYNDAEERRL FYVALTRAKK
     HVWVCANPDK TSPFINELIE DKYPVNNKIK RTK
//