ID A0A1Y7VJT0_MOUSE Unreviewed; 263 AA.
AC A0A1Y7VJT0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Zinc finger, FYVE domain containing 21 {ECO:0000313|Ensembl:ENSMUSP00000152558.2};
DE Flags: Fragment;
GN Name=Zfyve21 {ECO:0000313|Ensembl:ENSMUSP00000152558.2,
GN ECO:0000313|MGI:MGI:1915770};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000152558.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000152558.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000152558.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000152558.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000152558.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR ProteomicsDB; 308011; -.
DR Antibodypedia; 28114; 127 antibodies from 23 providers.
DR Ensembl; ENSMUST00000223211.2; ENSMUSP00000152558.2; ENSMUSG00000021286.9.
DR AGR; MGI:1915770; -.
DR MGI; MGI:1915770; Zfyve21.
DR VEuPathDB; HostDB:ENSMUSG00000021286; -.
DR GeneTree; ENSGT00940000159639; -.
DR ChiTaRS; Zfyve21; mouse.
DR Proteomes; UP000000589; Chromosome 12.
DR Bgee; ENSMUSG00000021286; Expressed in interventricular septum and 253 other cell types or tissues.
DR ExpressionAtlas; A0A1Y7VJT0; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15727; FYVE_ZF21; 1.
DR Gene3D; 2.30.29.160; Zinc finger FYVE domain-containing protein 21, C-terminal; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR032031; ZFYVE21_C.
DR InterPro; IPR038632; ZFYVE21_C_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR39490; ARRESTIN DOMAIN-CONTAINING PROTEIN D; 1.
DR PANTHER; PTHR39490:SF8; ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16696; ZFYVE21_C; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|EPD:A0A1Y7VJT0,
KW ECO:0007829|MaxQB:A0A1Y7VJT0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 55..110
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000152558.2"
SQ SEQUENCE 263 AA; 28917 MW; 86E62105EA388CB5 CRC64;
XGGGVRGSGG DMSSGVAARR DAKKLVRSPS GLRMVPEHRA FGSPFGLEEP QWVPDKECPR
CMQCDAKFDF ITRKHHCRRC GKCFCDRCCS QKVPLRRMCF VDPVRQCADC ALVSHREAEF
YDKQLKVLLS GATFLVTFGD SEKPETMVCR LSNNQRCLVL DGDSHREIEI AHVCTVQILT
EGFTPGEKDI HTYTSLLGSL LASEAGSTRA TGMLLQYTVP GAEAAAQLRL MAGEDASGSK
RQAAAWLAAM HKATKLLYES RDQ
//
