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Database: UniProt
Entry: A0A1Y9GKE8_ANOAR
LinkDB: A0A1Y9GKE8_ANOAR
Original site: A0A1Y9GKE8_ANOAR 
ID   A0A1Y9GKE8_ANOAR        Unreviewed;      1813 AA.
AC   A0A1Y9GKE8;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   31-JUL-2019, entry version 12.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:AARA016383-PA};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016383-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016383-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840,
RC   ECO:0000313|VectorBase:AARA016383-PA};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AARA016383-PA}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|VectorBase:AARA016383-PA};
RG   VectorBase;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
CC   -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
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DR   EMBL; APCN01002368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; AARA016383-RA; AARA016383-PA; AARA016383.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR   Gene3D; 3.10.20.360; -; 1.
DR   InterPro; IPR032940; CAMSAP.
DR   InterPro; IPR031372; CAMSAP_CC1.
DR   InterPro; IPR022613; CAMSAP_CH.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR038209; CKK_dom_sf.
DR   InterPro; IPR014797; CKK_domain.
DR   InterPro; IPR011033; PRC_barrel-like_sf.
DR   PANTHER; PTHR21595; PTHR21595; 1.
DR   Pfam; PF17095; CAMSAP_CC1; 1.
DR   Pfam; PF11971; CAMSAP_CH; 1.
DR   Pfam; PF08683; CAMSAP_CKK; 1.
DR   SMART; SM01051; CAMSAP_CKK; 1.
DR   SUPFAM; SSF47576; SSF47576; 1.
DR   SUPFAM; SSF50346; SSF50346; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS51508; CKK; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075840};
KW   Microtubule {ECO:0000256|PROSITE-ProRule:PRU00841};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075840}.
FT   DOMAIN       38    176       Calponin-homology (CH).
FT                                {ECO:0000259|PROSITE:PS50021}.
FT   DOMAIN     1672   1806       CKK. {ECO:0000259|PROSITE:PS51508}.
FT   REGION      224    317       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      329    520       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      627    652       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      746    847       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      866   1019       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1100   1167       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1179   1269       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1355   1378       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1419   1447       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1491   1551       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1598   1668       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      583    607       {ECO:0000256|SAM:Coils}.
FT   COILED      698    718       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    231    255       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    263    288       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    295    316       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    344    364       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    392    411       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    424    442       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    473    505       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    627    646       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    746    777       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    785    847       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    866    896       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    909    930       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    946    986       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1109   1167       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1179   1202       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1233   1258       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1358   1373       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1491   1505       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1524   1551       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1813 AA;  199682 MW;  BC54BD9D12C237EA CRC64;
     MTVIEALMVL YAKEVASSGR ISSALERISG CSVAPTVQHH EAALLNWISH VCGALKKRID
     YELTANGGGG AAAVDEYGQR HQSPNVPPVR DFRELCDGVC LAYLISYYCP KLVPWHSVKF
     NHVPTITDSI HNILIVSNFS ERSLPYTVFH MSPEDITYMR GSMKQNLVVL LADLFNLFEI
     HPAKCVCYPG MEQQSPDATG AGATNEHGIA HRRGFANQPT IAAIPDLRPG LDSPSSSSGG
     GGGGSGTSSG GNGGAGGVGC SSASGNGAIN RPPFQVNRSP SASTLRKHMS SREIPEQPQH
     QPHQLYQQQQ SPYQQADPDE GFVVHRSKGV PTLSSMQEPL VPARIRQAKE KTNNDSKAEE
     RGDSIPAGRP SNWEESRKTS FSGRRSRRNS FSDDSQLTIE NFGGSQDQLN TVGRFERERK
     ISNTSLTSIE QVAPTRSSLA DARGSIQFGY DTDSGNEKQD RDTEKLPGSA GGTLRRHNST
     TLHSTSSPMS HSSDVSNNAG SRAGSSSVER DLVDGDGTPT MGGSVGGIAV AAAATVSDVE
     LTPRRKTSFA TLPNTTTWQQ QAISVQKMDD VDDSQPLEDA SKISTIKLKL EEKRRLIEQE
     KRRIETAWTR QLQTVGKQAF LQAISKSKSG SNVAGEPEPT SKESNDGATV VEDDEVVVEK
     AERPCSLKDL DDHSKYEQKW NAQIIEPKKT PDLENMDLEQ YQADIQRLTQ QQSQIQAQTL
     QAQQLLHAQQ IANLLNQQYG SQQSIPTNTY RPMNTQMFGS SPHLPQHQQQ SSPINYGMRP
     PSRDPYLHQQ QQQQQHTMQY INDQGQYVQP QTNYGHHPNS NSHLVYSREQ SQTQLINDHN
     GGGNQYRTMT KESHQYSSNP YLNMEVHQQQ QQQQQFYHQD SNHYRDPYQP QQPQHHPQEL
     KEQHGGGQFF LHDNNNSTPP QPTQRRTWAQ SAAAAGVPLG GSPIITGRND NINSSMVDVN
     AWNHGPKQQG GTLPGYNKSS PAPASGGFSL HHNGGDGDSG YGGGSGRGGS GGSGGSQQSF
     QNLFEVHHPH HNMGGTGASP QHSKVRNQIS QMMISNGNNS PLASGGVGPM MGGGDYRDNR
     SMPLSPPIDD MAPQSISFIG DEDTGDIEIN TSKGGSRNDS FAMRQQHQQQ QQQQLDAMYG
     SSKGPAGMRN NNNNNNSHNN SAGGNVQDLD KHLSKLNITS GNRTYRIPSP TRPSLNSNSF
     HDPQEDVNEK GFYISFDNEQ PKRPKPPLRT KRSPKKDKPL ASDSNDGDKR RDSMIEKPSS
     RETNANNFGT YSVKTASSFS SSFNEEHNAS HARKSIIADN SGVSPFEPVV HKVNVTGSGA
     AAPSSPMMMM HHQQQQQQHH HPMDHLGDRR YTMEDHSISG NGHYSSHNNS SDGYGSETER
     KAKIVIDVSN DQTSVDEMER KKEKIMLLSL QRRQQAEEAK ARKEIEAMQR REKEREKEEE
     RARKKEEQFA RRQAILEAHK LKKAIEEAER EGKTIDRELQ LKHQMYQQQL HQTAHSTTPT
     PVAKLRTQKL TRPRPKTIHV ESGSVDLSEA SSLSSRGKKG SNSNLTGLGM HSASNTIRRD
     YYRGSQDSLA IREPATIERG RTLSRISLAK GANFRGRKSN SLMNLCDSDS GLGRATPPRR
     APSPGMGPSS RHLPSPSGPG SLPPGLITKR RGFDDGSSDI SSNASSMMDY NGPRLYKQPA
     TKSNRGIILN AVEYCVFPGA VNRDAKQKVL EKIARSEAKH FLVLFRDAGC QFRALYGYWP
     ENEQIIKLYG TGPSQVDDVM FDKFFKYNSG GKCFAQVHTK HLTVTIDAFT IHNSLWQGKK
     ANLPSKKDMA LVI
//
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