ID A0A1Y9H2H1_9DIPT Unreviewed; 976 AA.
AC A0A1Y9H2H1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Ras-associating domain-containing protein {ECO:0000259|PROSITE:PS50200};
OS Anopheles dirus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7168 {ECO:0000313|EnsemblMetazoa:ADIR015689-PA, ECO:0000313|Proteomes:UP000075884};
RN [1] {ECO:0000313|Proteomes:UP000075884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WRAIR2 {ECO:0000313|Proteomes:UP000075884};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Walton C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles dirus WRAIR2.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ADIR015689-PA}
RP IDENTIFICATION.
RC STRAIN=WRAIR2 {ECO:0000313|EnsemblMetazoa:ADIR015689-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A1Y9H2H1; -.
DR STRING; 7168.A0A1Y9H2H1; -.
DR EnsemblMetazoa; ADIR015689-RA; ADIR015689-PA; ADIR015689.
DR VEuPathDB; VectorBase:ADIR015689; -.
DR OrthoDB; 5354728at2759; -.
DR Proteomes; UP000075884; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd16134; RA_RASSF8; 1.
DR InterPro; IPR033593; N-RASSF.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR048945; RASSF8/10_RA.
DR InterPro; IPR048944; RASSF8_RA.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR15286:SF6; GH01133P; 1.
DR PANTHER; PTHR15286; RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF21712; ASPP1-2_RA; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1..82
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 79..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 764..791
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 871..926
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 129..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 104814 MW; 57850CACBD907544 CRC64;
MELKVWVEGI QRIVCGVTEV TTCQDVVFAL AHATGKTGRF TLIERWRNNE RLLAPHENPL
KILMKWGEYS SDVQFILQRS DQQQQQQQQK KDPQQHQQQH QTPPTTQITP QSQQQLLRQQ
QKLNQLNNNH IGVNGKHSGP TSPTSPSNNN NNNTSPATII PNGVLSAHNH INNNNSQHYQ
THHPSNGGDE QQQTHQHHHT QQHAKSKLHQ NNLKNSANSQ LLHHVHQQQQ QQHHHQHQLS
SSSTSSDHQH RHHHHQQQQH HPQPPNGVGA LIRTGNDPAS GGSPGGVGGA AAAKQSELII
ASAGGPTATA AAAAALERGK ETRKSLNSSG SSGGGKTEQK HHHHHQAQQQ NQNVGVVRGI
VQHQEKFGHV SGGTVQQRHS PNSAANVSKS ASGTVNATAT NTSAPTSDHS SSSSSSTSST
SSSSSNASSN NTSTSSGIGG SGGSGASGSS GHHHHHHHQT QQQQQQQQQP VEATYASVIK
KPKANASAAA AAAASSASSS NVVGEFNAAD LRSSLDRKVN GLVFSNGLNE RVTTSPSAAA
PPGQPPASII VGATLKQDHH QHPQHGGGTM GRPHYHHHTQ LQNLLCTDNQ HQHLDTSSVS
SISGSSIGGG NSSHASLLNG AGGAGSTTSS PITGISSNGA LVPPPYRDPP PPRNSPLSHN
TLTSLSSTGS GSTGRRHEKE GGGSGGGPTG GSSSASSTVS SLVVLGPGGL EDEGRPPDGP
VGGPHVTGYR ELMQLIKLQR EKINTQQADL SKYDTEIGYL ESRSREQTDQ LDALTQEISK
TEQQYRQTGD QLQAFQYVEE ESELVRQQEK TLKSEITLLR SKLANCETEL LQCKNKIRLL
MDEILVEQRK YSRQYDPNRQ QLLERALMCE VDRLQVEIDL AVQSADQANK THDKLKGEVT
LLEGAIADKK KQVEKLVHEM KEVNLQSLAV VPPADEVRHL LEVGSVKPGS TRRMIGSPRQ
LENAVPTSKN PHGVWV
//
