ID A0A1Y9H9K1_9DIPT Unreviewed; 360 AA.
AC A0A1Y9H9K1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=WW domain-binding protein 4 {ECO:0008006|Google:ProtNLM};
OS Anopheles farauti.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=69004 {ECO:0000313|EnsemblMetazoa:AFAF021724-PA, ECO:0000313|Proteomes:UP000075886};
RN [1] {ECO:0000313|Proteomes:UP000075886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FAR1 {ECO:0000313|Proteomes:UP000075886};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles farauti FAR1 (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AFAF021724-PA}
RP IDENTIFICATION.
RC STRAIN=FAR1 {ECO:0000313|EnsemblMetazoa:AFAF021724-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCN02002273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1Y9H9K1; -.
DR STRING; 69004.A0A1Y9H9K1; -.
DR EnsemblMetazoa; AFAF021724-RA; AFAF021724-PA; AFAF021724.
DR VEuPathDB; VectorBase:AFAF021724; -.
DR OrthoDB; 38440at2759; -.
DR Proteomes; UP000075886; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR000690; Matrin/U1-C_Znf_C2H2.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR013085; U1-CZ_Znf_C2H2.
DR InterPro; IPR040023; WBP4.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR13173; WW DOMAIN BINDING PROTEIN 4; 1.
DR PANTHER; PTHR13173:SF10; WW DOMAIN-BINDING PROTEIN 4; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF06220; zf-U1; 1.
DR SMART; SM00456; WW; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS50171; ZF_MATRIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 11..42
FT /note="Matrin-type"
FT /evidence="ECO:0000259|PROSITE:PS50171"
FT DOMAIN 168..201
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 107..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 225..278
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 107..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 41240 MW; F8FD124F8368F542 CRC64;
MADYWKSNDR KYCDFCKCWI ADNKSSIQFH ENGKRHQQNV QKRISEISRN SYKAQQEQHK
IDADLKKMND AAMKAYMQDI SAGADISSRE LHEQQKCELA NQIAAQESSL AGPSSNISSA
TDAKRPRPKK GREADPLYLP GIESDEESES SKGKTIAKKR RTDETANAAN ESMWVEAEND
DGFPYYWNVK TGESIWEPPK EGYMKKEEYE KLSKIAWQKQ KENAESEAKY ELENADEIAA
RLRRENMAQI FKHNRKIKEE LEKKVDHARE AATTAEIQRS KNPYGTWETV EAKPAQSIDL
QLPTAPAPLY VPSAAPEKTE PKFKEKVIDH VPLEAKATVS DSFIKKRKVQ RNARQRLDVD
//
