ID A0A1Z1WM14_9ACTN Unreviewed; 1183 AA.
AC A0A1Z1WM14;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=SARP family transcriptional regulator {ECO:0000313|EMBL:ARX87420.1};
GN ORFNames=SMD44_06901 {ECO:0000313|EMBL:ARX87420.1};
OS Streptomyces alboflavus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67267 {ECO:0000313|EMBL:ARX87420.1, ECO:0000313|Proteomes:UP000195880};
RN [1] {ECO:0000313|EMBL:ARX87420.1, ECO:0000313|Proteomes:UP000195880}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MDJK44 {ECO:0000313|EMBL:ARX87420.1,
RC ECO:0000313|Proteomes:UP000195880};
RA Wang Y., Du B., Ding Y., Liu H., Hou Q., Liu K., Wang C., Yao L.;
RT "Streptomyces alboflavus Genome sequencing and assembly.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP021748; ARX87420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z1WM14; -.
DR STRING; 67267.GCA_000716675_03606; -.
DR KEGG; salf:SMD44_06901; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR Proteomes; UP000195880; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000195880};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 36..133
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 36..133
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1183 AA; 126774 MW; 4C70E7236788FCCF CRC64;
MILTADAAPK HRGAPGPYDR GKGGHDLRGS GWSRVGTVRQ YGPVHIMMLG PFEVRTAAGA
AVEVPGTRLR ALLSALALEP GRVVTRTRLV DWIWGERPPA DEANALQVLV SRLRRVLPEG
SVEAESGGYR LAVAADAVDV SRFERLLGRA RAADDVARRA ELLRSALELW RGAALADIAP
HGSDAFVAAA TRLDELRLAA LADRVDADIR LGRGAGLVSE LTELVATHPL REGLVAALMR
ALAEAGRGSE ALMAYQKLRE RLVEALGVEP SAELSALHTA LLRGNVGDVG DGADAGARRP
YGERADRTSG AARASRPDRA PHVEAASPAE TTDPIRRTPH TWRTGSASHA VGGAGPADRD
EREQTGRGPR DGPAEPQRPR TNLRAGLTSF VGKDEDVAAV ADLITEHRLV TLTGPGGSGK
TRLAAETARR MLGDLPDGAW LVELASVRAG GELAQVVLTA IGLRDQALVG GGAGGDAGGG
LGGDSMDRLV AAVRERAHLL VLDNCEHMIE AAAAFADRLL GECRGLRVLA TSREPLGITG
EALWQVEPLA LPGAGADPDA VGASPAVLLL RDRAGAVRKD VVFDESTLAA MARICRALDG
IPLAIELAAA RLRTMSVEQL ALRLDDRFRL LSSGSRTALP RHKTLRAVVD WSWDLLTEAE
RSVLGRLSVF SGGATLDAAE RVCGGAALDG EQVLDVLTAL IEKSLLLADD TAVPRYRMLD
TIREYAAHRL AEAGETESAR RAHLAYFTEL TATAEPHLRR TEQLEWLAVL EAEHDNINAA
LRGAVADGWA HEAMRLVGPA GWYWFLSGRK AEGTELSVAA ASLDGPVPDD VRAMAYAVVT
LFLTSGQGDQ YAAQDWIHEA YRFARRGTSR HPLMVMVDLM ERMLAEPLEF LAAFEPMLTD
EDSWVRAQAR LNRSRLRLTV GRVEPDTDRD MEIALAEFRA LGDRWGMSLA LMSLADRLAQ
RGAFTEACAH YEQGITALTE LGALEDALGL RARQAQLYWL LGDEAACEAA MAEAQACVDR
VAWPDALAEL VLAKAQLARW RGRRDEAYAH LDAARTLRVS GTRGYLRVVT QDLYGYLAED
VDEARGHWAE AFREAVKLGH LPLLAHVLVG VADLALRQGR HERAVALLAA GESVRGTPDR
SLPDVDRITA AARARLGETA YADAVLAGRA GGWREQAEAT LAG
//
