ID A0A1Z2KWJ8_9ACTN Unreviewed; 421 AA.
AC A0A1Z2KWJ8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Polyketide beta-ketoacyl synthase {ECO:0000313|EMBL:ARZ66341.1};
GN Name=actI1 {ECO:0000313|EMBL:ARZ66341.1};
GN ORFNames=SMD11_0675 {ECO:0000313|EMBL:ARZ66341.1};
OS Streptomyces albireticuli.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1940 {ECO:0000313|EMBL:ARZ66341.1, ECO:0000313|Proteomes:UP000195755};
RN [1] {ECO:0000313|EMBL:ARZ66341.1, ECO:0000313|Proteomes:UP000195755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MDJK11 {ECO:0000313|EMBL:ARZ66341.1,
RC ECO:0000313|Proteomes:UP000195755};
RA Wang Y., Du B., Ding Y., Liu H., Hou Q., Liu K., Yao L., Wang C.;
RT "Streptomyces albireticuli Genome sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP021744; ARZ66341.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z2KWJ8; -.
DR KEGG; salj:SMD11_0675; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000195755; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 2..416
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 421 AA; 44833 MW; AEFB67BD42870A77 CRC64;
MTRRVVITGI GIRAPGGKGA KEFWSTLTNG RTATRRITFF DPSPYRSQVA AEADFDPVIE
GLTAPEIDRM DRATQFAVVC AKEAVRDSGL GFGGLDPYRV GVALGSAVAA ATSLEREYLA
LSGRGRDWEM DPARLSPHMF DYMAPSVMAA EVAWTVGAEG PVAMVSNGCT SGLDSVGHAA
QLIREGSADV MVAGACDTPI TPIVVACFDA IKATTPRNDD PEHASRPFDG SRNGFVLAEG
AAMFVLEEYD SARRRDAHIY AEVTGYATRS NAFHMTGLKP DGREMAEAIR VALDESRADV
TAVDYINAHG SGTKQNDRHE TAAFKRSLGQ HAYETPVSSI KSMVGHSLGA IGSVEIAASL
LAIEHNVVPP TANLHTSDPE CDLDYVPVTA REHRVDTVLT VGSGFGGFQS AMVLRSPQEV
S
//
