ID A0A1Z2L6X5_9ACTN Unreviewed; 648 AA.
AC A0A1Z2L6X5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Succinate dehydrogenase {ECO:0000313|EMBL:ARZ70040.1};
GN Name=sdhA {ECO:0000313|EMBL:ARZ70040.1};
GN ORFNames=SMD11_4438 {ECO:0000313|EMBL:ARZ70040.1};
OS Streptomyces albireticuli.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1940 {ECO:0000313|EMBL:ARZ70040.1, ECO:0000313|Proteomes:UP000195755};
RN [1] {ECO:0000313|EMBL:ARZ70040.1, ECO:0000313|Proteomes:UP000195755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MDJK11 {ECO:0000313|EMBL:ARZ70040.1,
RC ECO:0000313|Proteomes:UP000195755};
RA Wang Y., Du B., Ding Y., Liu H., Hou Q., Liu K., Yao L., Wang C.;
RT "Streptomyces albireticuli Genome sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP021744; ARZ70040.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z2L6X5; -.
DR KEGG; salj:SMD11_4438; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000195755; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 47..452
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 513..647
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 341
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 648 AA; 71481 MW; 0D91DD71D646D4AA CRC64;
MSDYTHYTTG EPVTDTAAPG GPIAERWDRR RFEAKLVNPA NRRKQTVIVV GTGLAGGAAG
ATLAEQGYHV VQFCYQDSPR RAHSIAAQGG INAAKNYRND GDSVHRLFYD TVKGGDFRAR
ESNVHRLAQV SVEIIDQCVA QGVPFAREYG GLLDTRSFGG VQVSRTFYAR GQTGQQLLLG
AYQALSRQID AGNVEMHART EMLDLIVVDG RARGIVARDL ITGDVGTYMA DAVVLASGGY
GNVFYLSTNA KNSNATAIWR AHRRGAHFAN PCFTQIHPTC IPRSGDHQSK LTLMSESLRN
DGRIWVPRAK GDTRPPASIP EDERDYYLER IYPSFGNLVP RDIASRAAKN VCDEGRGVGP
GGQGVYLDFA DAITRMGRKA VEAKYGNLFE MYERITAENP YEVPMRIYPA IHYTMGGLWV
DYDLQTTVPG LFAIGEANFS DHGANRLGAS ALMQGLADGY FVLPATINDY LARHPHTPVD
PAHPAVTEAV EGVTARLARL LAVDGDRTPD SFHRELGELL WDECGMARTD TGLRKALGRI
PALREEFWRR VKVPGTGEEL NQSLEKANRI FDYLELAELM CLDALHRTES CGGHFREESR
TPEGEAARKD DTFSYAAAWE FTGTGRAPVL HKEELTFEYV HPTQRSYA
//
