ID   A0A1Z2TMZ8_9EURY        Unreviewed;       253 AA.
AC   A0A1Z2TMZ8;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=acetate--CoA ligase (ADP-forming) {ECO:0000256|ARBA:ARBA00012957};
DE            EC=6.2.1.13 {ECO:0000256|ARBA:ARBA00012957};
GN   ORFNames=CDI07_05755 {ECO:0000313|EMBL:ASA77820.1};
OS   Thermococcus sp. 5-4.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=2008440 {ECO:0000313|EMBL:ASA77820.1, ECO:0000313|Proteomes:UP000196843};
RN   [1] {ECO:0000313|EMBL:ASA77820.1, ECO:0000313|Proteomes:UP000196843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-4 {ECO:0000313|EMBL:ASA77820.1,
RC   ECO:0000313|Proteomes:UP000196843};
RX   PubMed=28628615; DOI=10.1371/journal.pgen.1006847;
RA   Cossu M., Badel C., Catchpole R., Daniele G., Marguet E., Barbe V.,
RA   Forterre P., Oberto J.;
RT   "Flipping chromosomes in deep-sea archaea.";
RL   PLoS Genet. 13:e1006847-e1006847(2017).
RN   [2] {ECO:0000313|Proteomes:UP000196843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-4 {ECO:0000313|Proteomes:UP000196843};
RA   Cossu M., Badel C., Catchpole R., Daniele G., Marguet E., Barbe V.,
RA   Forterre P., Oberto J.;
RT   "Flipping Chromosomes in Deep-Sea Archaea.";
RL   PLoS Genet. 0:0-0(2017).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetate + ATP + CoA = acetyl-CoA + ADP + phosphate;
CC         Xref=Rhea:RHEA:15081, ChEBI:CHEBI:30089, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288,
CC         ChEBI:CHEBI:456216; EC=6.2.1.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001619};
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DR   EMBL; CP021848; ASA77820.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z2TMZ8; -.
DR   KEGG; thh:CDI07_05755; -.
DR   OrthoDB; 18103at2157; -.
DR   Proteomes; UP000196843; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT   DOMAIN          26..62
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   253 AA;  28614 MW;  0319DD48AFE4C2A1 CRC64;
     MKEEALKVIE EVLKSGRTSL VEYEAKQVLK AYGLPVPEEK LAKTLDEALK YAEEIGYPVA
     MKLMSPQILH KSDAKVVLLN IKTPEELKEK WEVIHENARK YRPDAEILGV LIAPMLKVGR
     EIIIGVTEDP QFGHALMFGL GGIFVEVLKD VTFRIIPITE RDARKMIQEI KSYPILAGAR
     GEEPADIDAI VELLLKVSEL VDDLDEYIKE MDLNPVFVYE KGKGAVVVDA RIIVKEPTEK
     KEEIITEYRE RCA
//