ID A0A1Z4BUF9_9GAMM Unreviewed; 1196 AA.
AC A0A1Z4BUF9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CEK71_01475 {ECO:0000313|EMBL:ASF44839.1};
OS Methylovulum psychrotolerans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylovulum.
OX NCBI_TaxID=1704499 {ECO:0000313|EMBL:ASF44839.1, ECO:0000313|Proteomes:UP000197019};
RN [1] {ECO:0000313|EMBL:ASF44839.1, ECO:0000313|Proteomes:UP000197019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HV10_M2 {ECO:0000313|EMBL:ASF44839.1,
RC ECO:0000313|Proteomes:UP000197019};
RA Mateos-Rivera A.;
RT "Genome Sequencing of the methanotroph Methylovulum psychrotolerants str.
RT HV10-M2 isolated from a high-altitude environment.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the hemerythrin family.
CC {ECO:0000256|ARBA:ARBA00010587}.
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DR EMBL; CP022129; ASF44839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z4BUF9; -.
DR KEGG; mpsy:CEK71_01475; -.
DR OrthoDB; 9804951at2; -.
DR Proteomes; UP000197019; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd12107; Hemerythrin; 1.
DR CDD; cd00130; PAS; 6.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.20.120.50; Hemerythrin-like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 6.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR035938; Hemerythrin-like_sf.
DR InterPro; IPR012827; Hemerythrin_metal-bd.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; NF033749; bact_hemeryth; 1.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR02481; hemeryth_dom; 1.
DR NCBIfam; TIGR00229; sensory_box; 6.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF3; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 3.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 6.
DR SMART; SM00091; PAS; 6.
DR SUPFAM; SSF47188; Hemerythrin-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 6.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 6.
DR PROSITE; PS50112; PAS; 5.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000197019}.
FT DOMAIN 259..305
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 330..384
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 465..516
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 517..570
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 592..648
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 649..704
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 720..772
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 773..844
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 846..897
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 891..939
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 966..1018
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1050..1188
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 1196 AA; 134781 MW; E8DCBB69A647D73B CRC64;
MICLRQDIPL VRWCCLFKLH FSISAYHSIF LYGGREKNVR SLPALSLSVH ITKKCDRQAF
NYKRISMDSI DIFPWNDNFK TGLPNIDEQH KKLVQLINRL ASHVAFQSDI PALNAIFDEL
ANYAVYHFDT EEAIWHRYFP EDALELGHKA THRHFIETIC QLKEDKANKS PEKVINEVLV
FLSRWLVAHI LENDRYLAMI VLAMQAGIPL EVAKQQADGQ MQGTTGTLID IIQSIYEGLS
TNTLALMREL MERRRDQESL RKLSLAVEQS PSSIVITDLN ANIEFVNEAF VKATGYSRTE
AQGNNPNLLQ SGKTPPQTYL NMWDTLLRGE VWQGEFINKR KDGSEYIELA LVSPVCQADG
VVTHYLAIKE DITERKRLER RLAEQLAFTQ AVIDAEVDGV AVCHSIAEPP YVHFTVWNPS
MESITGFSLE EINRLGWYQT VYIDPDTQQR AKQRMERMRQ GEHIQGEEWT ITHKDGGHRT
VQIFTTLCAQ DADGAHVLAV MHDITKRKRA EVALRESNQL LHSLLNSIAE GAYGVDTHGN
CTFVNRAFLR ILGYENTDEI IGKHIHELIH HSYPDGRPYP ASECRMYAAY KRNQEIHVEQ
EVFWRKDGTA VPVEYWSQPI ITDGVMIGAI ATFVDISERK KAEEASQLAA QYARSLIEAS
LDPLVTINGE GKITDVNTAT EQVTGVPRDS LIGSDFADYF TDPEQARRGY QQVFSQGAVT
DYPLAIRHTS GKVTDVLYNA TVYHDGNGKV LGVFAAARDI TERKQIEAKL ISSEYRLRTI
IDNEPECIKI IDARGLIVMM NPAGLAMLEA EHLDQVLGKT VLSAIAPKYR KAYTELHEQV
LAGHTAQMQY EITGFKGGCR WLETHAVPMK ESDGSVVHLA VTRDITERKR AEQQLRIAAT
VFESQEGMMV TDADQVILRV NKAFTDITGY TAEEAVGKTP RILQADRQDH SVYTSMWAKI
NATGAWEGEI WSRRKNGETY PEYLTITAVK DQDGMVSHYV GTLTDITLKK AAAEEIEKLA
FYDPLTGLPN RRLLYDRIKS ALAASHRNNR KGALLFIDLD NFKTLNDTLG HDMGDLLLQQ
VAGRLSACVR ENDTVARLGG DEFVVMLQDL DDEGDAAVQQ TAAVGHKILL TLNQPFRLTE
YDYSSTPSIG ATVFNAYGQS VEELLKNADI AMYNAKTSGR NTLRFFDPQM QAIVHN
//
