ID A0A1Z4C2X5_9GAMM Unreviewed; 372 AA.
AC A0A1Z4C2X5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:ASF47864.1};
GN ORFNames=CEK71_18320 {ECO:0000313|EMBL:ASF47864.1};
OS Methylovulum psychrotolerans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylovulum.
OX NCBI_TaxID=1704499 {ECO:0000313|EMBL:ASF47864.1, ECO:0000313|Proteomes:UP000197019};
RN [1] {ECO:0000313|EMBL:ASF47864.1, ECO:0000313|Proteomes:UP000197019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HV10_M2 {ECO:0000313|EMBL:ASF47864.1,
RC ECO:0000313|Proteomes:UP000197019};
RA Mateos-Rivera A.;
RT "Genome Sequencing of the methanotroph Methylovulum psychrotolerants str.
RT HV10-M2 isolated from a high-altitude environment.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022129; ASF47864.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z4C2X5; -.
DR KEGG; mpsy:CEK71_18320; -.
DR OrthoDB; 582216at2; -.
DR Proteomes; UP000197019; Chromosome.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ASF47864.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000197019};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:ASF47864.1}.
FT DOMAIN 37..117
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 139..350
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 280
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 372 AA; 40859 MW; A7B068E489FCDC33 CRC64;
MPLQKNPGAV RRFAKLMQFA AWLQSIPNKL TPPPFRLIQI GSAFWQSRAL HVAVRLDIAS
VLADKTLSAA AIAAHIGASA DAVHRLLRML SAMGIFTEQP PGSFRNNRLS AYLREDNPQN
VRAMILMHNS PEMSVPWYEQ LEQGMRNDEV PFQLAHGDTL YGYMDSHAEF DRLFTRAMAS
VEALTGDSFA TDFDWRQFDR VIDVGGSQGN KSVALLKRHP HLSALVFDRS QVIQAAANHW
AEQAPPSLLA RLAFQAGDLL ESVPSANNDR DIYLLSAVLH GMDDGACVKA LGNLASACAG
TGARIALLEW VVAKNQADFA SAAFDMQMFM ATRGRERTLA QWRHLFGQSG LALEEVVGLQ
SIGKLLVLKP QG
//
