ID A0A1Z4EE86_9MYCO Unreviewed; 437 AA.
AC A0A1Z4EE86;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:BAX91273.1};
DE EC=2.4.2.4 {ECO:0000313|EMBL:BAX91273.1};
GN Name=deoA {ECO:0000313|EMBL:BAX91273.1};
GN ORFNames=MSG_01114 {ECO:0000313|EMBL:BAX91273.1};
OS Mycobacterium shigaense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=722731 {ECO:0000313|EMBL:BAX91273.1, ECO:0000313|Proteomes:UP000217736};
RN [1] {ECO:0000313|Proteomes:UP000217736}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UN-152 {ECO:0000313|Proteomes:UP000217736};
RA Fukano H., Yoshida M., Kazumi Y., Ogura Y., Mitarai S., Hayashi T.,
RA Hoshino Y.;
RT "Complete Genome Sequence of Mycobacterium shigaense.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
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DR EMBL; AP018164; BAX91273.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z4EE86; -.
DR KEGG; mshg:MSG_01114; -.
DR Proteomes; UP000217736; Chromosome.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0009032; F:thymidine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:BAX91273.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BAX91273.1}.
FT DOMAIN 347..421
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 437 AA; 45422 MW; 042AF6CF8C60EE9A CRC64;
MSDLISDAAF DAPTVIRTKR DGGRLTDAAI DWVIGAYTDG HVADEQMAAL LMAIFWRGMD
EGEIARWTAA MVASGERMDF RDLCHGGTPL RTVDKHSTGG VGDKTTLALV PIVAACGVAV
PKASGRGLGH TGGTLDKLEC IPGFRVEVSN ERLQQQLCEV GAAIFAAGQL AAADKKLYAL
RDITATVESL PLIASSVMSK KLAEGVGALV LDVKVGAGAL LDSEAQCRAL AHTMVDLGAA
HGVPTRALLT DMNWPLGATV GNALEVAEAM EVLAGGGPAD VVELTLRLAG EMLDLVAIDD
RDPAQTLRDG TAMDRFRRLV AAQGGDLSVP LPIGAHSETV TAGRGGTMGD IDAMAVGLTA
WRLGAGRSRP GEAVQPGAGV RIHRRPGEPV TPGEPLFTLY TDTPERFGAA MAELDGAFSV
GDAAPTPRPL IIDRIVT
//
