ID A0A1Z4ENV5_9MYCO Unreviewed; 309 AA.
AC A0A1Z4ENV5;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB {ECO:0000313|EMBL:PRI14896.1};
DE SubName: Full=Putative tRNA/rRNA methyltransferase {ECO:0000313|EMBL:BAX94693.1};
GN ORFNames=B2J96_10445 {ECO:0000313|EMBL:PRI14896.1}, MSG_04578
GN {ECO:0000313|EMBL:BAX94693.1};
OS Mycobacterium shigaense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=722731 {ECO:0000313|EMBL:BAX94693.1, ECO:0000313|Proteomes:UP000217736};
RN [1] {ECO:0000313|EMBL:PRI14896.1, ECO:0000313|Proteomes:UP000239044}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UN-152 {ECO:0000313|EMBL:PRI14896.1,
RC ECO:0000313|Proteomes:UP000239044};
RA Yoshida M., Fukano H., Hoshino Y.;
RT "Draft genome sequence of Mycobacterium shigaense sp. nov.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000217736}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UN-152 {ECO:0000313|Proteomes:UP000217736};
RA Fukano H., Yoshida M., Kazumi Y., Ogura Y., Mitarai S., Hayashi T.,
RA Hoshino Y.;
RT "Complete Genome Sequence of Mycobacterium shigaense.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:BAX94693.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 32072 {ECO:0000313|EMBL:BAX94693.1};
RA Yoshida M., Fukano H., Ogura Y., Kazumi Y., Mitarai S., Hayashi T.,
RA Hoshino Y.;
RT "Complete Genome Sequence of Mycobacterium shigaense.";
RL Genome Announc. 6:e00552-18(2018).
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
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DR EMBL; AP018164; BAX94693.1; -; Genomic_DNA.
DR EMBL; MWON01000011; PRI14896.1; -; Genomic_DNA.
DR KEGG; mshg:MSG_04578; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000217736; Chromosome.
DR Proteomes; UP000239044; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:BAX94693.1};
KW Transferase {ECO:0000313|EMBL:BAX94693.1}.
FT DOMAIN 69..145
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 32592 MW; 66C283DBC33527F5 CRC64;
MAGNSRRQGA IRKSGSKKGP TVGSGGQRRR GLEGRGPTPP AHLRPNHPAA KRAQSQQRRP
AKRTDDTETV LGRNPVLECL RAGVPATALY VALGTEADER LTESVGRAAD LGIAILEVPR
LDLDRMTANH LHQGIALQVP PYNYAHPDDL LATALQSPPA LLVALDNISD PRNLGAIVRS
VAAFGGHGVL IPQRRSASVT AVAWRTSAGA AARLPVARAT NLTRTLKDWA ERGVRVVGLD
AGGHTVLDDL DGTDSMVVVV GSEGKGLSRL VRQNCEQVVS IPMAGDTESL NASVAAGVVL
AEIARQRRH
//
