ID A0A1Z4RB20_9CYAN Unreviewed; 1874 AA.
AC A0A1Z4RB20;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=NIES4101_56340 {ECO:0000313|EMBL:BAZ39680.1};
OS Calothrix sp. NIES-4101.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Calotrichaceae;
OC Calothrix.
OX NCBI_TaxID=2005461 {ECO:0000313|EMBL:BAZ39680.1, ECO:0000313|Proteomes:UP000290974};
RN [1] {ECO:0000313|EMBL:BAZ39680.1, ECO:0000313|Proteomes:UP000290974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-4101 {ECO:0000313|EMBL:BAZ39680.1,
RC ECO:0000313|Proteomes:UP000290974};
RA Hirose Y., Shimura Y., Fujisawa T., Nakamura Y., Kawachi M.;
RT "Genome sequencing of cyanobaciteial culture collection at National
RT Institute for Environmental Studies (NIES).";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP018280; BAZ39680.1; -; Genomic_DNA.
DR Proteomes; UP000290974; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:BAZ39680.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000290974};
KW Transferase {ECO:0000313|EMBL:BAZ39680.1}.
FT DOMAIN 11..273
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1605..1862
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 855..882
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1566..1593
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1874 AA; 211049 MW; DAFF5D9E65AF7DC3 CRC64;
MVTTIIDIPG YRVCTPLYDG SRTVVYRAFR KTDSLAVVIK LLKNPYPSFQ ELVQFRNQYT
IVKNFNFPGI IQAHSLEPFE NSYALVMEDF GGISIKNYFT HIETRNIRFL QEFLQIAIAL
CDILDELHRH RVIHKDIKPA NILINQDTKQ VKLIDFSIAS LLPKEAQEIK SPNVLEGTLA
YISPEQTGRM NRGIDYRSDF YSLGVTFYEL LTRQLPFQSD EPMELVHFHI AKTAEPIKNP
AIPQVIADIV MKLMAKNAED RYQSALGLKH DLEKCLSQLH KLGHEIREIT YFEIGKRDTC
DRFLIPEKLY GRENEVQELL AAFDRSAGIS HNYPHDYHHS DSLGGKTNVK PLNLSQQTKL
GSQGKAELIL VAGFSGIGKT AIVNEVHKPI VQQRGYFIKG KFDQFNRNIP LDAFVQAFRD
LIGQLLCESD AQLQSWKLRI LEALGENAQV IIDVIPELAQ IIGEQSPAPE LSGTAAQNRF
NLLFQKFIQV FTKPEHPLVM FLDDLQWADS ASLNLIQLLM AESGTGYLLM IGAYRDNEVF
AAHPLMLTLD AIAKTGTKIN TITLKPLSES SLNQLVADTL KSAITLVQPL TKLVYQKTQG
NPFFATQFLK ALHQEQLITF DPQARHWQCD IARVREAALT DDVVEFMALQ LQKLPEATQN
VLKLAACIGN QFDLNTLAIV AEESTIDMAT ALWSALQEGL ILSKSEIYKF YIGEVVENVQ
VNTEIADYKF LHDRVQQAAY SLIPEAEKPA THLKIGQLLF NESSTYTNNA TIFEIVNQLN
LGRQLIQELP AIWQLAELNV TAGRQAKQST AYSSAVDYFQ TAIQLLTASV WERDYSLALS
LYTDIIEATY LNGDFERMEQ LLSELQKQAK NNLDLIKAQE IQIEALVAQG KLRESLNLGL
GILAQFGIKF PETPTLEDYT TALQRARQAI GDRVAALQEH YQSAELIDLP LATDEQAIAV
MRVLVKLAAP AFLASPPLYP LLPYCGVELS ARVGISGAST YLFACYGLLH CAILNDYRAG
YEFGQLALAL CNKLADQEFQ ARAFLMNGLF ITHWTGHLRD SLPQLQSGYT TGLDTGDSAY
TSYSAYSYCF FAYFSGQPLP ELIPEIERYK QVIQRLNQGT ILNYHNIYHQ IVLNLSGESH
CSISTLVGDV YNEAEMLPLH QSANDYVALA ILFINKLILS VWFGNWEIAL ENSEMAEKYL
GGAAAVASIP LYYFYDSLTR LTYAHKLAPA DSREYNLRIQ QNLEKLTTWA EYAPMNHQHK
LDLVKAEQHR FLQQNSEAIE LYDRAIVGAK ENGYLQEEAF ANELAAKFYL DWGKEKVAAG
YMQEAYYCYT RWGAKAKIAH LEENYPQLLA AILQVPTFPF NHEGTIASTV MRSVTNVSST
HNSWLDFPVV MKAAQAISQE IALDKLLATL MQTTIAAAGA EIGRLILRQD KQWFVVAQAN
AQQTQRLEIP LGEFAEIPQS LIYTVARSQE TAVFENLSAL VRFAGDRYIS SQQPKSVLCT
PISQQGKVIG ILYLENNLTV GAFTSDRLQV IQLLTTQAAI SLENAQLYCQ LEEYSHTLEQ
KVSQRTQELT QKATQLELTL QELQRTQTQL IQSEKMSSLG QLVAGIAHEI NNPVNFIHGN
INHVKQYMQD LLYLVNISQQ SNSHPIQTSE LVTEIDLDFI QEDLPKTLKS MEVGTERIRE
IVLSLRTFSR MDEAEFKKVD IHTGIDSTIM ILQHRLKETS ERPAIQIIKN YNKLPLVECY
AGQLNQVFMN ILTNAIDAIT EKNSKLHFAE IATTPNQITI RTLVIDNDWI EIAIADNGIG
IPEKVKHKVF NPFFTTKPVG KGTGMGMSIS YQIITEKHGG KLECFSMLNQ GTEFVIKIPI
RQEESKKIST LSLI
//
