ID   A0A1Z4RD51_9CYAN        Unreviewed;       409 AA.
AC   A0A1Z4RD51;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:BAZ40385.1};
GN   ORFNames=NIES4101_63460 {ECO:0000313|EMBL:BAZ40385.1};
OS   Calothrix sp. NIES-4101.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Calotrichaceae;
OC   Calothrix.
OX   NCBI_TaxID=2005461 {ECO:0000313|EMBL:BAZ40385.1, ECO:0000313|Proteomes:UP000290974};
RN   [1] {ECO:0000313|EMBL:BAZ40385.1, ECO:0000313|Proteomes:UP000290974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-4101 {ECO:0000313|EMBL:BAZ40385.1,
RC   ECO:0000313|Proteomes:UP000290974};
RA   Hirose Y., Shimura Y., Fujisawa T., Nakamura Y., Kawachi M.;
RT   "Genome sequencing of cyanobaciteial culture collection at National
RT   Institute for Environmental Studies (NIES).";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; AP018280; BAZ40385.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z4RD51; -.
DR   Proteomes; UP000290974; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF7; ALCOHOL DEHYDROGENASE (ZN-DEPENDENT)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290974};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          8..321
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   409 AA;  43682 MW;  2AD49DA07FDCDF6C CRC64;
     MKAVVFHGIG DIRLDNVPEP KIKQPTDAII RLTSSAICGT DLHMIRGTFT GMKPGTILGH
     EGVGIIEEIG SNVRNFKVGD RVVVPSTIAC GYCSYCRTGY QAQCDNANPH GHNAGTAFFG
     GPEAAGPFDG LQAEYARIPY ANTGLVKLPK EVTDDQAILL SDIFPTAYFG ADIAEITPGD
     TVAIFGCGPV GQFAIVSARL FGAGRIIAVD TIPSRLEMAR DLGAEVIDYN AEDPIEAIRE
     LTGGIGVDRV IDAVGVDANA PDSGPAAEKA RKEAQQFQQQ LQQIAPKTNP QNGNWHPGNA
     PSQVLEWAVQ ALAKAGTLSI IGVYPPSHNF FPIGMAMNKN LTINMGNCNH RKYIPTLVDL
     VRNGTVDPTK VLTQIEPLMS VLDAYKAFDK RQPGWVKVEL VPGKALANV
//