ID A0A1Z4V2E3_9CYAN Unreviewed; 566 AA.
AC A0A1Z4V2E3;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Cobalamin biosynthesis precorrin-3 methylase {ECO:0000313|EMBL:BAZ85686.1};
GN ORFNames=NIES806_18900 {ECO:0000313|EMBL:BAZ85686.1};
OS Dolichospermum compactum NIES-806.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC Dolichospermum; Dolichospermum compactum.
OX NCBI_TaxID=1973481 {ECO:0000313|EMBL:BAZ85686.1, ECO:0000313|Proteomes:UP000218702};
RN [1] {ECO:0000313|EMBL:BAZ85686.1, ECO:0000313|Proteomes:UP000218702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-806 {ECO:0000313|EMBL:BAZ85686.1,
RC ECO:0000313|Proteomes:UP000218702};
RA Hirose Y., Shimura Y., Fujisawa T., Nakamura Y., Kawachi M.;
RT "Genome sequencing of cyanobaciteial culture collection at National
RT Institute for Environmental Studies (NIES).";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; AP018316; BAZ85686.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z4V2E3; -.
DR OrthoDB; 9772960at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000218702; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:BAZ85686.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 52..131
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 316..527
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 566 AA; 60397 MW; F4009768F98E387C CRC64;
MNIRVCPAVV VLSQNSVTVG RKITNVLAGA KLYGLVNRTH DVDITFTNFG ETLRELFAAG
TPIIGICAAG ILIRTIAPLL TDKGQEPPVL AVAEDGSAVV PLLGGLSGVN DLARQVGSAL
NIQPAITTTG DIRFHTALLS PPAGYHLANP EHGKKFIADL LAGGKVKLQG IAHWLSESNL
PIDENGELII QITENLGNSD ANCLVYHPGK IAIALTSPEP DTITQIHQIL AASNLAPAAV
AGIFAPLQLA NNSQLHSIAT TLGVPTRFLH TNELTELVLA ATGADSRIVS SPFSQIAVAI
STQIINPDTI GQPQGKLAII GTGPGASQWM SPQVKEILAS ATDLVGYKTY INLIGHLADG
KRIHESDNRV EAERAYQALD LAASGKYVAV VSSGDPGIYA MAAAVFEVLE QYHKPEWQTI
DIQVAPGISA MQAAAATIGA PLGHDFCVIS LSDILKPWEI IAQRITAAAK SDFVIAFYNP
VSKERTWQLA AAKKILMEHR KPNTPVVLGR NLGRKGEEVK VTTLKELEPA LADMRTVIII
GSSHTRQIQQ DHNIWVYTSR RYNSQE
//
