ID A0A1Z4V9S1_9CYAN Unreviewed; 1166 AA.
AC A0A1Z4V9S1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=NIES806_44080 {ECO:0000313|EMBL:BAZ88174.1};
OS Dolichospermum compactum NIES-806.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC Dolichospermum; Dolichospermum compactum.
OX NCBI_TaxID=1973481 {ECO:0000313|EMBL:BAZ88174.1, ECO:0000313|Proteomes:UP000218702};
RN [1] {ECO:0000313|EMBL:BAZ88174.1, ECO:0000313|Proteomes:UP000218702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-806 {ECO:0000313|EMBL:BAZ88174.1,
RC ECO:0000313|Proteomes:UP000218702};
RA Hirose Y., Shimura Y., Fujisawa T., Nakamura Y., Kawachi M.;
RT "Genome sequencing of cyanobaciteial culture collection at National
RT Institute for Environmental Studies (NIES).";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP018316; BAZ88174.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z4V9S1; -.
DR REBASE; 207263; Dco806ORF44080P.
DR Proteomes; UP000218702; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR046816; MmeI_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF20473; MmeI_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 522..605
FT /note="MmeI-like DNA-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF20473"
SQ SEQUENCE 1166 AA; 133637 MW; 5B39308CD72495D6 CRC64;
MIGVQFEGNL LAADITTELL TGNIKGQTPA DFGLPKSDKL EDEIAIAWGD AKAYWASFQR
QLNRLDAEDT ATSITREMAV LLLKSLGYTP VYTAKAEVVE GQTYGISHRA VSPSDSSITN
YELPITNYPP IHIIGCRLDI DKRPPSGTPR LSAHGLVQEY LNKTEHLWAI ATNGFRWRLL
RDSSLMTRLT YIEFDLEQIL NGENFAEFGL FYRLFHRSRL PETADDADKC LLEYYHQESL
QQGGRVRDRL RDGVEKALIQ LGNGFIQHRD SENLCQKYSD NYELRITNYE LIYYRQLLRL
IYRLLFLMVA ESRNLLLIGE DTEKARIYLE YYSIERLREL AERPRYRREG FQDIWQGLRV
TFKLFDENWR GQILGLSPLN GDLFGSQTLT DLNNCGIDNY DLLTAIRCLS LYEDKGQTRR
VNYAALDVEE LGSVYESLLD FHPQIKQNQG IYEFNLVFGS DRKTTGSYYT PPQLVQQLIK
TALEPVIEEK LRQAEQKTSN SNNYELQTTN SKFQIPNYEL RITNYELSLL SIKVIDPACG
SGHFLLAAAR RIGKELAKVR TGESQPAPEP LRQAVRDVIQ NCIYGVDLNP LAVDLCKVAL
WIEGFATGKP LNFLDHRIKC GNSLVGVLDL DCLDAGIPDD AFKAVTGDDK KLATDFKKRN
KKERENQGQL SIFETAADDS YIFAKLWQEL ADFSENTPQE VKEKERKYQD NLLDNHWWLK
KAACNLWTAA FFMYLTEHNL QLLPTTATID RLKRETVQKV LNSDSNYELR ITNYELQGLI
DAANKLAQEK NFFHWPLEFP EVFNPQPENS SNYELRITNY ELPKGFDCVL GNPPWERIKL
QEKEFFASRN LDIANAQNKA AREKLIKELP KKNPALAQAF EDAKHDAEAQ SKFIREGGRF
PLTAVGDINT YAVFAETTRS LISVNGRVGV IVPTGIATDD TCKKFFGDLI QKQNLASLYD
FENREKLFAA VDSRMKFSLL ALSGKPIKRG NFAFFLTQPK QLENQTRLFQ LSPQDIALIN
PNTLTCPVFR TSKDAELTKK IYQNVPVLEN EKTGINPWGI SFMAMFHMAN DSGLFQNEAG
DNLLPLYEAK MFHQFDHRWA TYTDNGDTRD LTDDEKSDLS FSVQPRYWVD RKEVENKLSG
KWDKNWLLGF RDITNSTNER TAIFSL
//
