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Database: UniProt
Entry: A0A1Z5HN86_9THEO
LinkDB: A0A1Z5HN86_9THEO
Original site: A0A1Z5HN86_9THEO 
ID   A0A1Z5HN86_9THEO        Unreviewed;       278 AA.
AC   A0A1Z5HN86;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   13-FEB-2019, entry version 5.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=KKC1_01450 {ECO:0000313|EMBL:GAW90983.1};
OS   Calderihabitans maritimus.
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Moorella group; Calderihabitans.
OX   NCBI_TaxID=1246530 {ECO:0000313|EMBL:GAW90983.1, ECO:0000313|Proteomes:UP000197032};
RN   [1] {ECO:0000313|EMBL:GAW90983.1, ECO:0000313|Proteomes:UP000197032}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KKC1 {ECO:0000313|EMBL:GAW90983.1,
RC   ECO:0000313|Proteomes:UP000197032};
RA   Omae K., Yoneda Y., Fukuyama Y., Yoshida T., Sako Y.;
RT   "Genomic analysis of Calderihabitans maritimus KKC1, a thermophilic
RT   hydrogenogenic carboxydotrophic bacterium isolated from marine
RT   sediment.";
RL   Appl. Environ. Microbiol. 0:0-0(2017).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAW90983.1}.
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DR   EMBL; BDGJ01000003; GAW90983.1; -; Genomic_DNA.
DR   BioCyc; GCF_002207765:KKC1_RS00650-MONOMER; -.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000197032; Unassembled WGS sequence.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000197032};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197032}.
FT   DOMAIN        2    181       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      194    271       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   278 AA;  30890 MW;  0F64B6381FE7A513 CRC64;
     MKLGYLGPQG TFSQQAAQRW IADKAGWELV SYESIPEVIL GVAEKRLDAA VVPVENSIEG
     TVNVTLDMLV EEKSLSIIGE VILEVHHHLI GKQTDWKRVQ AIYSHPQALA QCRGFLRQNF
     QGVSLRTAAS TAEAARIVAS GPDSWAAISS RFAAELYGLQ VLAENIEDYR GNKTRFITVG
     RGPVKPTGKD KTSMVLALPQ DRPGGLYRVL EEFAAEEINL TKIESRPTKK ELGEYLFFLD
     CEGHATDPKL SRVLDRLRRK TALLRILGSY PRDMGEQK
//
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