ID   A0A1Z5I9R5_9LACO        Unreviewed;       472 AA.
AC   A0A1Z5I9R5;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Arginine/ornithine antiporter {ECO:0000313|EMBL:GAW98546.1};
GN   Name=arcD_1 {ECO:0000313|EMBL:GAW98546.1};
GN   ORFNames=IWT30_00491 {ECO:0000313|EMBL:GAW98546.1};
OS   Secundilactobacillus mixtipabuli.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Secundilactobacillus.
OX   NCBI_TaxID=1435342 {ECO:0000313|EMBL:GAW98546.1, ECO:0000313|Proteomes:UP000198374};
RN   [1] {ECO:0000313|EMBL:GAW98546.1, ECO:0000313|Proteomes:UP000198374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IWT30 {ECO:0000313|EMBL:GAW98546.1,
RC   ECO:0000313|Proteomes:UP000198374};
RA   Tohno M., Tanizawa Y., Arita M.;
RT   "Draft genome sequences of new species of the genus Lactobacillus isolated
RT   from orchardgrass silage.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2)
CC       family. {ECO:0000256|ARBA:ARBA00008220}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAW98546.1}.
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DR   EMBL; BCMF01000002; GAW98546.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z5I9R5; -.
DR   OrthoDB; 9762947at2; -.
DR   Proteomes; UP000198374; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR004754; Amino_acid_antiprt.
DR   NCBIfam; TIGR00905; 2A0302; 1.
DR   PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR42770:SF4; ARGININE_ORNITHINE ANTIPORTER-RELATED; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   PIRSF; PIRSF006060; AA_transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198374};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        236..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        279..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        447..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   472 AA;  51453 MW;  57AEB4C866DA126D CRC64;
     MESSENKIGL FPLVGIIIGA IVGAGIFNLM KEMASTASVG VTIIGWIIAG TGMGSLALCM
     ESLNSKRPDL NAGIFSYAQE GFGDYIGFNS IWGYWVSVII GNVAFGTLLF SALGYFFPVF
     GNGQNIASII GASIMLWVLH FMIIRGLDKA ALLNAVVMVA KLVPISIFII CIIAGFNKQI
     FFHDFWGTLA SNGQASGSIM TQLKGTVLAT VWVFIGVEGA VVFSGRAKKR SDVGKATILG
     FGAVALIYAA VTVLSFGVMT QDQLRHLPNP AMAYVLEHVI GKPGAILVNL GVIIAIFGAW
     IANTLLAEEV AYQASLKQLF PKVFKKENKH DMPVNSTFIT NLIVQVLLLS FLVTDQAYSL
     LSKLSSATIL LPYTCVALYQ LKVDFQTKES PLSKNVIVGV IATLYMFWLI YASGIMYIVL
     TILSLVPGTI MYAYVRKKYK HKVFNKYEIV IFVIFLIMFA YGVWQLPTII KM
//