ID A0A1Z5J963_FISSO Unreviewed; 475 AA.
AC A0A1Z5J963;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000313|EMBL:GAX10525.1};
DE EC=3.4.24.64 {ECO:0000313|EMBL:GAX10525.1};
GN ORFNames=FisN_21Lh232 {ECO:0000313|EMBL:GAX10525.1};
OS Fistulifera solaris (Oleaginous diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Naviculaceae;
OC Fistulifera.
OX NCBI_TaxID=1519565 {ECO:0000313|EMBL:GAX10525.1, ECO:0000313|Proteomes:UP000198406};
RN [1] {ECO:0000313|EMBL:GAX10525.1, ECO:0000313|Proteomes:UP000198406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCC DA0580 {ECO:0000313|EMBL:GAX10525.1,
RC ECO:0000313|Proteomes:UP000198406};
RX PubMed=25634988; DOI=10.1105/tpc.114.135194;
RA Tanaka T., Maeda Y., Veluchamy A., Tanaka M., Abida H., Marechal E.,
RA Bowler C., Muto M., Sunaga Y., Tanaka M., Yoshino T., Taniguchi T.,
RA Fukuda Y., Nemoto M., Matsumoto M., Wong P.S., Aburatani S., Fujibuchi W.;
RT "Oil accumulation by the oleaginous diatom Fistulifera solaris as revealed
RT by the genome and transcriptome.";
RL Plant Cell 27:162-176(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX10525.1}.
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DR EMBL; BDSP01000017; GAX10525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5J963; -.
DR InParanoid; A0A1Z5J963; -.
DR OrthoDB; 167798at2759; -.
DR Proteomes; UP000198406; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:GAX10525.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198406}.
FT DOMAIN 52..200
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 205..390
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 475 AA; 52458 MW; 18B79FCD8ABF3108 CRC64;
MALRASLGKF ASRTIQRARV SSAAVAASTP QFPDYVLRAP TTDVTTLDSG LRVASETVQG
SETATVGVWI DAGSRYETAA NNGVAHFLEH LSFKGTSKRT QQQLEVEIEN MGGHLNAYTS
REQTVYFAKV FKNDLKKAVE ILSDILLHSK LDEGAIERER DVILREMSEI NKQQEELVLD
HLHATAYQGT GLGRTILGPE ENIRSLTRKD LVDYIQQHYT APRMVIAAAG AVQHAELCDL
ASEYFGNVPT VPAGGLGVAM DPAIFTGSDY LVKFNSEDTA HIALAYETAS WTSEYAFPLL
LMQGMLGSYD RTQGLGRNHA SRLGQEVAEN ELAHSYAAFN SCYKDTGLFG LYMVCPDNKV
DDMMWTVMNN LVRLVHSPSD EEVERAKLNL KATMLAGLDG HANTAEDIGR QLLTYGRRMT
PAEIFSRIDA VTVDDIKATA AKFINDQDHA LAAVGGIHEL PDYNWIRSHS YWLRY
//
