ID A0A1Z5KC78_FISSO Unreviewed; 262 AA.
AC A0A1Z5KC78;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Prolyl 4-hydroxylase {ECO:0000313|EMBL:GAX23806.1};
DE EC=1.14.11.2 {ECO:0000313|EMBL:GAX23806.1};
GN ORFNames=FisN_20Hh006 {ECO:0000313|EMBL:GAX23806.1};
OS Fistulifera solaris (Oleaginous diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Naviculaceae;
OC Fistulifera.
OX NCBI_TaxID=1519565 {ECO:0000313|EMBL:GAX23806.1, ECO:0000313|Proteomes:UP000198406};
RN [1] {ECO:0000313|EMBL:GAX23806.1, ECO:0000313|Proteomes:UP000198406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCC DA0580 {ECO:0000313|EMBL:GAX23806.1,
RC ECO:0000313|Proteomes:UP000198406};
RX PubMed=25634988; DOI=10.1105/tpc.114.135194;
RA Tanaka T., Maeda Y., Veluchamy A., Tanaka M., Abida H., Marechal E.,
RA Bowler C., Muto M., Sunaga Y., Tanaka M., Yoshino T., Taniguchi T.,
RA Fukuda Y., Nemoto M., Matsumoto M., Wong P.S., Aburatani S., Fujibuchi W.;
RT "Oil accumulation by the oleaginous diatom Fistulifera solaris as revealed
RT by the genome and transcriptome.";
RL Plant Cell 27:162-176(2015).
CC -!- COFACTOR:
CC Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
CC Evidence={ECO:0000256|ARBA:ARBA00001961};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX23806.1}.
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DR EMBL; BDSP01000204; GAX23806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5KC78; -.
DR InParanoid; A0A1Z5KC78; -.
DR OrthoDB; 34881at2759; -.
DR Proteomes; UP000198406; Unassembled WGS sequence.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
DR GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.60.120.620; q2cbj1_9rhob like domain; 1.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR InterPro; IPR045054; P4HA-like.
DR InterPro; IPR006620; Pro_4_hyd_alph.
DR InterPro; IPR044862; Pro_4_hyd_alph_FE2OG_OXY.
DR PANTHER; PTHR10869:SF207; P4HA_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10869; PROLYL 4-HYDROXYLASE ALPHA SUBUNIT; 1.
DR Pfam; PF13640; 2OG-FeII_Oxy_3; 1.
DR SMART; SM00702; P4Hc; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:GAX23806.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198406}.
FT DOMAIN 145..250
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 262 AA; 29820 MW; C859522781E63DC4 CRC64;
MNKMFERIVA TAPGNRTLTD AERKELAADN MTEYTVTVHS RPSDEPSTEI SVVVDKSLPP
WVITFDNFLL PEECDALIAL GYKYEYKRSQ DVGAAKFDGS HEGVQSTRRT SENAWCSDHH
GCRKEELAVK IHERMSKVMG IPPENSEDLQ MLKYEKGQFY RTHHDYIPHQ KDRQCGPRIL
TFFLYLSDVE EGGGTNFPQL NITVMPKKGR ALLWPSTLNA DPMVKDGRTS HQAMDVIEGT
KFATNGWVHM YDYVTPQKKG CN
//
