ID A0A1Z5KD73_FISSO Unreviewed; 1398 AA.
AC A0A1Z5KD73;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Phosphatidylinositol 4-kinase A {ECO:0000313|EMBL:GAX23898.1};
DE EC=2.7.1.67 {ECO:0000313|EMBL:GAX23898.1};
GN ORFNames=FisN_20Hh104 {ECO:0000313|EMBL:GAX23898.1};
OS Fistulifera solaris (Oleaginous diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Naviculaceae;
OC Fistulifera.
OX NCBI_TaxID=1519565 {ECO:0000313|EMBL:GAX23898.1, ECO:0000313|Proteomes:UP000198406};
RN [1] {ECO:0000313|EMBL:GAX23898.1, ECO:0000313|Proteomes:UP000198406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCC DA0580 {ECO:0000313|EMBL:GAX23898.1,
RC ECO:0000313|Proteomes:UP000198406};
RX PubMed=25634988; DOI=10.1105/tpc.114.135194;
RA Tanaka T., Maeda Y., Veluchamy A., Tanaka M., Abida H., Marechal E.,
RA Bowler C., Muto M., Sunaga Y., Tanaka M., Yoshino T., Taniguchi T.,
RA Fukuda Y., Nemoto M., Matsumoto M., Wong P.S., Aburatani S., Fujibuchi W.;
RT "Oil accumulation by the oleaginous diatom Fistulifera solaris as revealed
RT by the genome and transcriptome.";
RL Plant Cell 27:162-176(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX23898.1}.
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DR EMBL; BDSP01000204; GAX23898.1; -; Genomic_DNA.
DR InParanoid; A0A1Z5KD73; -.
DR OrthoDB; 147843at2759; -.
DR Proteomes; UP000198406; Unassembled WGS sequence.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05168; PI4Kc_III_beta; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF22; PHOSPHATIDYLINOSITOL 4-KINASE BETA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:GAX23898.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198406};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:GAX23898.1}.
FT DOMAIN 1106..1382
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT REGION 269..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..726
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..872
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..887
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1398 AA; 155014 MW; 2FA90C2F36848226 CRC64;
MNVISSSYYS ATRKDGVCSG TLWRQKEPVS GSSSELGASL NSLSISVSSS ASPEARSCDY
CILVGCRLEC YESQLVWSRR DPPNVVFYVV GASASIKDTY EISFRLVSNQ GTHLLCQATS
KECRNVWLAA FQAGLELSLG DFISEPTLLP PEPQAQIKRF VRSNRSYCVS CGAVEGGKPP
VASPVKTNSS SIASINLVGT KSIGSNVAPM TQYGYEGKVD LCEDCATAQG LLQHVEFYKL
LLQAAQHEQR VLEKARELCW KTVLASEPQM KSDLSENDGS EEPIEEDTKD NSGSTESWSQ
VDRDTDGTPS PPDSWQSVED SPNMKQSWIH LPPNSASTVA LLEVVRDPLE FGRLATASPF
LESLCKNLED GVIGAPDFLE QLDEKTKKRK ESHESVAALK KQAFRVSGDL GCAMKLLLES
ALSSPSRRGS AQDDILICIL DFLLELCEEG ETSTVGFYWP QICQIHLRML PAANIAEARR
IELYEDFLIT VSCRYSVHLA LDLVWSHTAD LEESLGNPSC STSCRRRRHA VLRFVCELES
VLFDFEGCWG GGSVSLRNML SPTGHQVQLL QERMQQIQEM RMRPTFELCR SGRMDLLLRT
QNELIPEEAV LEKLRVAKNA DYFSCHLNFT RRLSDIAEKL RHKDVSERAS ILEQELESLN
SSGTMGGDPL NRVRDDYIRV MRIPSTEGHV FRSKERTPVL LLMEVVDEGA SKEEEKLDEK
QRAYQQEDIS EANTCTEESE GGDVLEPFHE RQRAETDETD ESPSASHLHT PKGTRKTSVL
EASGSRPRTP RKDVEDIVNS VAVQALKDIV LPDIKASSNM EADVTATLNE ISLEDEVEIN
ADNETGLADS DIKGEESGDL VKSTRKKTAT RGLLDSKQGS FDDSHNSLAP TGDVRRDVLN
AIMLRGMQGN SIAAGTAISI QRSLQELERK RATELLLRNE KEGSSDEDKS SLPQLIAKDD
AQPAQTCEED EVMESIRLLL IQTRVAQGKL SAIDAAKVLQ HVSLNRVASG NNIGDEEPGN
DGSEEEEVTT IDAGDIDPRL VGCGPVPPAV LKALTLWKGG MVNNAELLEL VKKDAAFIRH
SVLLDSENVD KLNEDSAFWG RFAFGERWAE KKSRILSSSP EGTLPGWDLL GVIVKSNDDL
RQEAFVMQLI ELCQEAFDLA GLELWVSPYR ILATGRTTGV IEMVRNAMSF DALKKRPGYG
KGGLREHFRR MTEFTADPSE AFRSAQMNFV RSLAAYSLMS YFFLFKDRHN GNLLLDTAGH
VIHIDFGFVF GIAPGGSFSL EMSTPFKLTE EMLDVMGGLR SSLFSEFVTL FCCGFLALQA
YRDTFLTIVE ITCEDSTFKC FEGKDTNEFL DKLRDRFCPN KTKEETVAFA LDLIKQATTS
YGTRQYDLYQ YMSQGIAA
//
