ID   A0A1Z5KTI1_FISSO        Unreviewed;       744 AA.
AC   A0A1Z5KTI1;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   28-JUN-2023, entry version 18.
DE   RecName: Full=Prolyl endopeptidase {ECO:0000256|RuleBase:RU368024};
DE            EC=3.4.21.- {ECO:0000256|RuleBase:RU368024};
GN   ORFNames=FisN_2Hh175 {ECO:0000313|EMBL:GAX29616.1};
OS   Fistulifera solaris (Oleaginous diatom).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Bacillariophyceae; Bacillariophycidae; Naviculales; Naviculaceae;
OC   Fistulifera.
OX   NCBI_TaxID=1519565 {ECO:0000313|EMBL:GAX29616.1, ECO:0000313|Proteomes:UP000198406};
RN   [1] {ECO:0000313|EMBL:GAX29616.1, ECO:0000313|Proteomes:UP000198406}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JPCC DA0580 {ECO:0000313|EMBL:GAX29616.1,
RC   ECO:0000313|Proteomes:UP000198406};
RX   PubMed=25634988; DOI=10.1105/tpc.114.135194;
RA   Tanaka T., Maeda Y., Veluchamy A., Tanaka M., Abida H., Marechal E.,
RA   Bowler C., Muto M., Sunaga Y., Tanaka M., Yoshino T., Taniguchi T.,
RA   Fukuda Y., Nemoto M., Matsumoto M., Wong P.S., Aburatani S., Fujibuchi W.;
RT   "Oil accumulation by the oleaginous diatom Fistulifera solaris as revealed
RT   by the genome and transcriptome.";
RL   Plant Cell 27:162-176(2015).
CC   -!- SIMILARITY: Belongs to the peptidase S9A family.
CC       {ECO:0000256|ARBA:ARBA00005228, ECO:0000256|RuleBase:RU368024}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAX29616.1}.
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DR   EMBL; BDSP01000293; GAX29616.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Z5KTI1; -.
DR   InParanoid; A0A1Z5KTI1; -.
DR   OrthoDB; 7264at2759; -.
DR   Proteomes; UP000198406; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR   PANTHER; PTHR42881:SF13; PROLYL ENDOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU368024, ECO:0000313|EMBL:GAX29616.1};
KW   Protease {ECO:0000256|RuleBase:RU368024};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198406};
KW   Serine protease {ECO:0000256|RuleBase:RU368024}.
FT   DOMAIN          8..239
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          532..738
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   744 AA;  82926 MW;  DC1C1CF6E49EC38B CRC64;
     MSTTTVSTAE DPYIWLEEVE SEQSLDFARS ANAACLAALG NPEEKGTYAR VLQILESDDR
     IPHVTHFGVN DDGEPILFNF WKDAKNPKGL WRYTTLSSYK KTSDIEWTTV LDVDALAEKD
     GISWVWGGSR PLPRSRDPVY SKDRVTRALI VLSRGGSDAT HVKEFDLTTN DFVTDQPFQL
     PEAKSRVSYK SRNVLLVGTD TGPDSLTDSG YPRTVREWVR GTDLLTDAKV VFEGETTDVS
     VSAFISDERI WGGGIYEVYS RAMTFYTSKY FVRSVQFEHL LAPDERGPYV SDPPDFVELD
     VQDDANISFL GKLLVITLRS DWEPVVGGPV YKKGSVIYTD AETFLQKGRT GCEYKILFEP
     TERTAYEYYS VTKNYLILST MDNVKSRLQF YKIEDGGSRL TLIEGGSQEA QIRDVGIRPI
     DPYSGSDEFW FTTSDFVTPS TLFLADASRM ETTNGESDAF IVEHVKSLPP QFDASGLVVS
     QCTATSKDGT QIPYFIVRKE DTVLNGKNPT LLYGYGGFEV SLGPHYVATQ GVAWLERGGV
     YVEANIRGGG EFGPSWHQAG LKANRNKCYE DFIAVGEHLI ETKVCSPKTL AVRGGSNGGL
     LVGNMYTMRP DLFGAIHCAV PLLDMKRFHT LLAGASWMAE YGNPDTDDWE FLQKYSPYHN
     IKEGTEYPPI LVTTSTRDDR VHPAHARKFV KKLMDGSNGK LPVYYYENIE GGHGGAADAK
     QSAFMTALAY DFMFDTLSKN AMEL
//