ID A0A1Z5R9S9_SORBI Unreviewed; 684 AA.
AC A0A1Z5R9S9;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0008006|Google:ProtNLM};
GN ORFNames=SORBI_3007G090472 {ECO:0000313|EMBL:OQU80185.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:OQU80185.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:OQU80185.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
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DR EMBL; CM000766; OQU80185.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5R9S9; -.
DR EnsemblPlants; OQU80185; OQU80185; SORBI_3007G090472.
DR Gramene; OQU80185; OQU80185; SORBI_3007G090472.
DR Proteomes; UP000000768; Chromosome 7.
DR ExpressionAtlas; A0A1Z5R9S9; baseline and differential.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF39; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 99..387
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 461..647
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 684 AA; 78505 MW; 85958B32BC225C5E CRC64;
MWRLKVAEGA GPWLKSSNNF RGRAVWEFDP ELGTPEERAE VERARREFTE RRFQKRESSD
LLLRLQYAKH KHLQVDPPPA KLAENEEVTE DIILAALRRA LAQHSSLQAD DGCWPADYSG
LLFIMPLLVF ALYTTGSLNT VLSKEHQREI RRYIYNHQNE DGGWGKQVLG PSTMFGSCLN
YVALRLIGED CTNVALTNGR EWILSHGSAT AIPQWGKIWF SVMGLYDWSG NNPVIPELWL
LPYFLPIHPG RFWILCRMVY LPMAYLFGKK FVGEVTPTIL ELRSELYSVP YSEVDWKKAR
DTCAKVDLIY PRTMAQNLVW TFLNKVIEPM LNWWPVNKLR DIALQNIMEH IHYEDETSKY
ICICPINKAL DMICCWAENP NSDAFKQHLP RIYDMLWLAE DGMKAQISEN HLDYKSYYRH
ASKGSWTLST ADNGCSISDC TAEALKALLL LSKISPDLVG EPIKGESLYD AVDCLLSFVN
NDGSFSAYEC KRTTPLLEVL NPSESFRNII VDYPCVECTS SVLQALIMFR DLDHVYRKEE
IGNCIERASR FIEKEQRKDG SWFGSWGICF TYGTFFAIKG LALSGRTYEN SDAIRKACSF
LLSKQLHTGG WGETYLSSET AEYVEASRPH AVNTAWAMLT LVYGGQEHVG CFNSSIFFNY
GNYRNLYPIW ALGEFRRRLL ERKK
//
