ID A0A1Z5RDZ3_SORBI Unreviewed; 354 AA.
AC A0A1Z5RDZ3;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=WAT1-related protein {ECO:0000256|RuleBase:RU363077};
GN ORFNames=SORBI_3006G082300 {ECO:0000313|EMBL:OQU81596.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:OQU81596.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:OQU81596.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363077}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU363077}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000256|ARBA:ARBA00007635, ECO:0000256|RuleBase:RU363077}.
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DR EMBL; CM000765; OQU81596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5RDZ3; -.
DR EnsemblPlants; OQU81596; OQU81596; SORBI_3006G082300.
DR Gramene; OQU81596; OQU81596; SORBI_3006G082300.
DR InParanoid; A0A1Z5RDZ3; -.
DR OMA; AWCMEMR; -.
DR Proteomes; UP000000768; Chromosome 6.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; WAT1-RELATED PROTEIN; 1.
DR PANTHER; PTHR31218:SF200; WAT1-RELATED PROTEIN; 1.
DR Pfam; PF00892; EamA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363077};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Transmembrane {ECO:0000256|RuleBase:RU363077};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363077}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 94..118
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 276..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT DOMAIN 7..147
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 354 AA; 38798 MW; 89AFD044AF6879CD CRC64;
MDDGTKPYIV AIIVRVIFAG MFVINKAAID HGLNSFVFIF YRQIAASLLM LPIAVLLERR
NARSMSSALL FKIFVCALIG ITFSGTLYNV SLKLTSATVV AASTNSIPVI TFCLALLLRM
EELKLRSPSG IAKLTGVALC LAGVLVIALY AGELLSAVNH HHAFVAAPTH AASATAPKTL
MGATWIKGTF MAAAVLKEFP NKMLVMVTQC LFSMVQSFLA AVVAERDFSM WKLHLDIGLL
AIFYSGFVVA GVNYYLQAWC MEMRGPVFLT AWTPLSFVLT MLCSSFFLGE MVHLGSMLWG
KSRETKTLQC NIETTTVDDG AQDGVHRELE GHKENKGREE QEKVELETCV HQQV
//
