ID A0A1Z5RFR1_SORBI Unreviewed; 679 AA.
AC A0A1Z5RFR1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Smr domain-containing protein {ECO:0000259|PROSITE:PS50828};
GN ORFNames=SORBI_3006G270200 {ECO:0000313|EMBL:OQU82584.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:OQU82584.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:OQU82584.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
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DR EMBL; CM000765; OQU82584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5RFR1; -.
DR EnsemblPlants; OQU82584; OQU82584; SORBI_3006G270200.
DR Gramene; OQU82584; OQU82584; SORBI_3006G270200.
DR OMA; IHAIIND; -.
DR Proteomes; UP000000768; Chromosome 6.
DR ExpressionAtlas; A0A1Z5RFR1; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR CDD; cd03280; ABC_MutS2; 1.
DR Gene3D; 3.30.1370.110; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002625; Smr_dom.
DR InterPro; IPR036063; Smr_dom_sf.
DR PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR48378:SF2; SMR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00488; MutS_V; 1.
DR Pfam; PF01713; Smr; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00463; SMR; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF160443; SMR domain-like; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
DR PROSITE; PS50828; SMR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 608..679
FT /note="Smr"
FT /evidence="ECO:0000259|PROSITE:PS50828"
FT REGION 562..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 408..435
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 679 AA; 74631 MW; 4D39EDC8648AB13F CRC64;
MLESLLKDTA AKIFQAGGID SPLVTKRRSR MCVGVKASHK HLVPGGIVLS SSGSGATYFV
EPRDAVELNN REVKLSGDER AEELAILSLL TSMIADSQLK IRNLMDKVLE LDLACARGSY
ARWTNGVKPT FSDSYTISQS DQCTDYSVYI EGIRHPLLLE QSLMAEESTT RASEMPVPLD
MWVKKHARIV VISGPNTGGK TATMKTLGLS SLMSKAGMFF PAKGSPRIPW FDQVLADIGD
HQSLEHSLST FSGHISRLRK IVEIVSKDSL VLIDEIGSGT DPSEGVALST SILKYLASKV
NLAIVTTHYA DLSRLQSVDN RFENAAMEFC VETLQPTYRI LWGSTGNSNA LSIAKSIGFD
QKVLDRAQEW VEKLLPDKQK ERQGLLYDSL LDEKKLLESQ ANEAASVLSQ VEGLYNEIRL
EADDLESRVA GLRARETQKV QQELKVVKSQ MDTIIKNFEA QLKNSKLEQY NSLMRKAEAA
TASVVAAHQP NEITFDDDEN QSSFVPQIGD KVYIQGLGGG TMATVVETFG EDESCMVQYG
KIKVRVKRNK IKLVQRGINN EATTSSSVKA KGRTPKQRSA TTAEADRNQD GGGSISFGPV
VQTSKNTVDL RGKRVSEAAY ELQMAIDACR TYQVLFVVHG MGTGAVKERA IDVLRNHPRV
AKFEDESPLN YGCTVAYIQ
//
