ID A0A1Z5RQI0_SORBI Unreviewed; 1952 AA.
AC A0A1Z5RQI0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00012589};
DE EC=2.4.1.34 {ECO:0000256|ARBA:ARBA00012589};
DE AltName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00032165};
GN ORFNames=SORBI_3004G358400 {ECO:0000313|EMBL:OQU86033.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:OQU86033.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:OQU86033.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->3)-
CC beta-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:21476, Rhea:RHEA-
CC COMP:11146, Rhea:RHEA-COMP:14303, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37671, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.34;
CC Evidence={ECO:0000256|ARBA:ARBA00000192};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 48 family.
CC {ECO:0000256|ARBA:ARBA00009040}.
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DR EMBL; CM000763; OQU86033.1; -; Genomic_DNA.
DR STRING; 4558.A0A1Z5RQI0; -.
DR EnsemblPlants; OQU86033; OQU86033; SORBI_3004G358400.
DR Gramene; OQU86033; OQU86033; SORBI_3004G358400.
DR eggNOG; KOG0916; Eukaryota.
DR InParanoid; A0A1Z5RQI0; -.
DR OMA; ITNFQWH; -.
DR OrthoDB; 211713at2759; -.
DR Proteomes; UP000000768; Chromosome 4.
DR GO; GO:0000148; C:1,3-beta-D-glucan synthase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0003843; F:1,3-beta-D-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046527; F:glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006075; P:(1->3)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR026899; FKS1-like_dom1.
DR InterPro; IPR003440; Glyco_trans_48.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR PANTHER; PTHR12741:SF103; 1,3-BETA-GLUCAN SYNTHASE; 1.
DR PANTHER; PTHR12741; LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1; 1.
DR Pfam; PF14288; FKS1_dom1; 1.
DR Pfam; PF02364; Glucan_synthase; 1.
DR Pfam; PF04652; Vta1; 1.
DR SMART; SM01205; FKS1_dom1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 532..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..692
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 721..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1513..1535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1564..1583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1682..1706
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1760..1778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1790..1811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1823..1846
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1852..1872
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1893..1915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 330..446
FT /note="1,3-beta-glucan synthase component FKS1-like"
FT /evidence="ECO:0000259|SMART:SM01205"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1952 AA; 225015 MW; ED27FEF8F4B5B8F8 CRC64;
MASSSGGGGG RRLAPGGDAS PASAGARRIY RTQTAGNLGD SIFDSEVVPS SLVEIAPILR
VANEVEASNP RVAYLCRFYA FEKAHRLDPT SSGRGVRQFK TALLQRLERE NDPTLKGRVK
QSDAREMQSF YQHYYKKYIQ ALQNAADKAD RAQLTKAYQT AAVLFEVLKA VNVSQKIEVD
QSILETHNQV EEKKKLYLPY NILPLDPDSA NQAIMRYPEI QAAFHALRNT RGLPWPKEHD
KKPDADLLAW LQAMFGFQKD NVSNQREHLI LLLANVHIRQ IPKPEQQPKL DDRALDTVMK
KLFKNYKRWC KYLGRKSSLW LPTIQQEVQQ RKLLYMGLYL LIWGEAANLR FMPECLCYIY
HHMAFELYGM LAGNVSPTTG ENVKPAYGGE EEAFLKRVVT PIYKVIEKEV ERSKTMKSKH
SHWRNYDDLN EYFWSRDCFR LGWPMRSDAD FFKTPNVSLH HLDGEDRPVG NGNWMGKVNF
VEIRSFWHIF RSFDRMWSFL ILSLQAMIII AWNGGTPSDI FDRGVFKQVL SIFITAAILK
LGQAILDIIL SWKARRNMSL VVKLRYILKL LSAAAWVVIL PVTYAYTWEN PTGLARTIKS
WLGDGQNQPS LYILAVVIYL APNLLSATLF LFPVIRRALE RSNLRVVTFI MWWSQPRLFV
GRGMHEGAFS LFKYTMFWVL LLATKLVVSF YVEIKPLVQP TKDIMKEPIR TFKWHEFFPH
ANNNIGVVIA LWAPIILVYF MDTQIWYAIF STLIGGVYGA CRRLGEIRTL GMLRSRFESL
PKAFNQCLIP SDTSKRRGFR AAFSKPSKTP EDTKEEEKIA ARFAQIWNLI ITSFREEDLI
DDREKDLLLV PYCKDRDMDI IQWPPFLLAS KIPIALDMAA DSGGKDRDLK KRMKSDPYFT
YAIKECYASF KNIIYALVIS SRERGFIQKI FDMVDEHITE ETLIKELNMS NLPTLSKKFI
ELLDLLESNN KEEQGQVIIL FQDMLEVVTR DIMVDQLSDL LESIHGPNNK RSEGMMPLDQ
QVQLFTKAID FPVKKTQAWN EKIKRLRLLL TVKESAMDVP TNLDARRRIS FFANSLFMSM
PDAPKVRQML PFSVLTPYYK EDVLFSSQAL GEQNEDGVSI LFYLQKIYPD EWKNFLERVH
CESEDQLHET EQSEEQLRLW ASYRGQTLTR TVRGMMYYRQ ALVLQAFLDM ARDDDLMEGF
RAADLLSESD ESQLLTQCKA IADMKFTYVV SCQQYGIQKR SGDPHAQDIL RLMTTYPSLR
VAYIDEVEEP SKDRNKKIEK VYYSALVKAA VTKPDDPGQK LDQDIYRIKL PGNAMLGEGK
PENQNHAIIF TRGEGLQTID MNQEHYMEET LKMRNLLQEF LKKHDGVRYP SILGVREHIF
TGSVSSLAWF MSNQETSFVT IGQRVLANPL RVRFHYGHPD IFDRLFHLTR GGVSKASKII
NLSEDIFAGF NSTLREGNVT HHEYMQVGKG RDVGLNQISL FEAKIANGNG EQTLSRDVYR
LGHRFDFFRM LSCYYTTIGF YFSTMITVWT VYVFLYGRLY LVLSGLDEAL ATGKRFIHNE
PLQVALASQS FVQLGFLMAL PMMMEIGLER GFRTALSDFV LMQLQLASVF FTFSLGTKTH
YYGTTLLHGG AEYRATGRGF VVFHAKFAEN YRLYSRSHFV KGIELMILLI VYEIFGQSYR
GAIAYIFITI SMWFMVVTWL FAPFLFNPSG FEWQKIVDDW TDWNKWISNR GGIGVPPEKS
WESWWEKEQE PLRHSGKRGT VLEIVLALRF FIYQYGLVYH LNITTHTKSV LVYCISWVII
FVILLVMKTV SVGRRKFSAE FQLVFRLIKG LIFITFISII IILIAIPHMT VQDIFVCILA
FMPTGWGLLL IAQTMRSAIS HMGLWGSVKA LARGYEIIMG LLLFTPIAFL AWFPFVSEFQ
TRMLFNQAFS RGLQISRILG GHKKDRAARN KE
//
