ID A0A1Z5SNN3_HORWE Unreviewed; 774 AA.
AC A0A1Z5SNN3;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=BTJ68_14590 {ECO:0000313|EMBL:OTA22452.1};
OS Hortaea werneckii EXF-2000.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX NCBI_TaxID=1157616 {ECO:0000313|EMBL:OTA22452.1, ECO:0000313|Proteomes:UP000194280};
RN [1] {ECO:0000313|EMBL:OTA22452.1, ECO:0000313|Proteomes:UP000194280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-2000 {ECO:0000313|EMBL:OTA22452.1,
RC ECO:0000313|Proteomes:UP000194280};
RA Sinha S., Flibotte S., Neira M., Lenassi M., Gostincar C., Stajich J.E.,
RA Nislow C.E.;
RT "The recent genome duplication of the halophilic yeast Hortaea werneckii:
RT insights from long-read sequencing.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTA22452.1}.
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DR EMBL; MUNK01000370; OTA22452.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5SNN3; -.
DR STRING; 1157616.A0A1Z5SNN3; -.
DR VEuPathDB; FungiDB:BTJ68_14590; -.
DR InParanoid; A0A1Z5SNN3; -.
DR OrthoDB; 2045814at2759; -.
DR Proteomes; UP000194280; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR47550; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR PANTHER; PTHR47550:SF1; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000194280}.
FT DOMAIN 568..726
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 645..713
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 84406 MW; 8CFC19168A8AB262 CRC64;
MAAQVCARPA PVPHQPASTT SSQLSINTSQ AGSPKAVPHK HIPYCSPGPR PTSHQLDTPP
ASPPESSQLV ETTSLLYPPS GFDKITNEPP IYSISAEKLS QAIDHLATQP LPAAEQVFPW
LHGLHPENQL QLAFFTARKK SLRRTPKCLR GLTIVKAGGD LSHSRLKGAI AADEILCPVK
PGRDRKSEEG DFLEVDPKDG FSVRNFHIQT CKMATVSDLV VYRDYQTPQE EAERLARRLA
RAQAAWQRKT DGSAFGGRMF NTFIVSDEYL KIEAVYPELI ALDSDGCMTT SALDFFHAER
VEMCSMTAAS EISHNVWLGP TPDPSVDLQS SALPSCSPSP KDPPFDIMIE ASDIAQIPEP
KAFKLLDDLL QRKANAELAE NAIPQLEFPG SGAILPPTWS QAEVDGLLAT CQWIYRQAHT
PPSSSSPRRG GAADANVADD LDEDGDIPMT SSSSSSSSPC SSQQGHRILI HCTDGYTESS
LLALAYYIFA EYVPVHDAWV RLHRDLGRNF FAYATDVALL RAIQPRLLQA SPKHCPSAGT
GGAGGLGDGM AALCPPTPEW LDKMDGSLPS RILDHLYLGN LGHANNPDLL RELGIGRVLS
VGEPVGWGCE DEGDGDEEEG GKGWKREDWM FVDQTQDNGV DPLMGQFGRC LEFIEQGRRN
GTSTLVHCRV GVSRSATICI AHVMQTLNLS FPKAYCFVRA RRLNVIIQPH LRFVWELMKW
EEVLQRRGEG EGGRGERGGD GMQGLEGDDG RVGGWEGASR GKWIGRVCVG RLLL
//
