ID A0A1Z5SSS7_HORWE Unreviewed; 371 AA.
AC A0A1Z5SSS7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};
GN ORFNames=BTJ68_13534 {ECO:0000313|EMBL:OTA23860.1};
OS Hortaea werneckii EXF-2000.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX NCBI_TaxID=1157616 {ECO:0000313|EMBL:OTA23860.1, ECO:0000313|Proteomes:UP000194280};
RN [1] {ECO:0000313|EMBL:OTA23860.1, ECO:0000313|Proteomes:UP000194280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-2000 {ECO:0000313|EMBL:OTA23860.1,
RC ECO:0000313|Proteomes:UP000194280};
RA Sinha S., Flibotte S., Neira M., Lenassi M., Gostincar C., Stajich J.E.,
RA Nislow C.E.;
RT "The recent genome duplication of the halophilic yeast Hortaea werneckii:
RT insights from long-read sequencing.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as component of the Arp2/3 complex which is
CC involved in regulation of actin polymerization and together with an
CC activating nucleation-promoting factor (NPF) mediates the formation of
CC branched actin networks. {ECO:0000256|PIRNR:PIRNR038093}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC {ECO:0000256|PIRNR:PIRNR038093}.
CC -!- SIMILARITY: Belongs to the WD repeat ARPC1 family.
CC {ECO:0000256|ARBA:ARBA00006260, ECO:0000256|PIRNR:PIRNR038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTA23860.1}.
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DR EMBL; MUNK01000272; OTA23860.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Z5SSS7; -.
DR STRING; 1157616.A0A1Z5SSS7; -.
DR VEuPathDB; FungiDB:BTJ68_13534; -.
DR InParanoid; A0A1Z5SSS7; -.
DR OrthoDB; 5471154at2759; -.
DR Proteomes; UP000194280; Unassembled WGS sequence.
DR GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
DR GO; GO:0005885; C:Arp2/3 protein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR017383; ARPC1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10709; ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR10709:SF2; ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT; 1.
DR Pfam; PF00400; WD40; 2.
DR PIRSF; PIRSF038093; ARP2/3_su1; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW ECO:0000256|PIRNR:PIRNR038093}; Cytoplasm {ECO:0000256|PIRNR:PIRNR038093};
KW Cytoskeleton {ECO:0000256|PIRNR:PIRNR038093};
KW Reference proteome {ECO:0000313|Proteomes:UP000194280};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 52..84
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 371 AA; 40150 MW; 7DD6F688458A9994 CRC64;
MSGAPETHHL FHAPISDHSF SSDRSTLAVC RDTNVELYSR NSSNRFQLAD ELRGHDKTIT
GVDIAPNSGR IVTCSQDRNA YVWEPSGNGG WKPTLVLLRI NRAATSVRWS PNEQKFAVGS
GARIIATCYF EEENDWWVSK HLKKPLRSTV TSVAWHPNSV LLAAGSADGH ARVLSAFIKG
VDERPEPSAW GERLPFNTVC GEFLNPTAGW VHDVAFSPSG NALAFVAHDS SVTVVYPSAP
EQPPSAIVSV TTQLLPFTSL LWTSEAELVA AGYDCGVYRF AGDQNGWKLT EALEKDSLSG
KTGGDGGGEQ SALNMFRSMD LKGRSGVVDD TKLKTVHQNS INTLRSYQEA GGNVSKISTS
GVDGRVVVWS L
//
