ID   A0A1Z5T6J3_HORWE        Unreviewed;      1291 AA.
AC   A0A1Z5T6J3;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   13-SEP-2023, entry version 17.
DE   RecName: Full=REM-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BTJ68_07307 {ECO:0000313|EMBL:OTA31588.1};
OS   Hortaea werneckii EXF-2000.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX   NCBI_TaxID=1157616 {ECO:0000313|EMBL:OTA31588.1, ECO:0000313|Proteomes:UP000194280};
RN   [1] {ECO:0000313|EMBL:OTA31588.1, ECO:0000313|Proteomes:UP000194280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-2000 {ECO:0000313|EMBL:OTA31588.1,
RC   ECO:0000313|Proteomes:UP000194280};
RA   Sinha S., Flibotte S., Neira M., Lenassi M., Gostincar C., Stajich J.E.,
RA   Nislow C.E.;
RT   "The recent genome duplication of the halophilic yeast Hortaea werneckii:
RT   insights from long-read sequencing.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the RICTOR family.
CC       {ECO:0000256|ARBA:ARBA00008878}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTA31588.1}.
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DR   EMBL; MUNK01000111; OTA31588.1; -; Genomic_DNA.
DR   STRING; 1157616.A0A1Z5T6J3; -.
DR   VEuPathDB; FungiDB:BTJ68_07307; -.
DR   InParanoid; A0A1Z5T6J3; -.
DR   OrthoDB; 90320at2759; -.
DR   Proteomes; UP000194280; Unassembled WGS sequence.
DR   GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   Gene3D; 1.10.287.160; HR1 repeat; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR011072; HR1_rho-bd.
DR   InterPro; IPR036274; HR1_rpt_sf.
DR   InterPro; IPR028268; Pianissimo_fam.
DR   InterPro; IPR028267; Pianissimo_N.
DR   InterPro; IPR029453; Rictor_IV.
DR   InterPro; IPR029451; RICTOR_M.
DR   InterPro; IPR029452; RICTOR_V.
DR   PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR   PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR   Pfam; PF02185; HR1; 1.
DR   Pfam; PF14663; RasGEF_N_2; 1.
DR   Pfam; PF14666; RICTOR_M; 1.
DR   Pfam; PF14664; RICTOR_N; 1.
DR   Pfam; PF14668; RICTOR_V; 1.
DR   SMART; SM01303; RasGEF_N_2; 1.
DR   SMART; SM01307; RICTOR_M; 1.
DR   SMART; SM01308; RICTOR_N; 1.
DR   SMART; SM01310; RICTOR_V; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF46585; HR1 repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000194280}.
FT   DOMAIN          229..594
FT                   /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01308"
FT   DOMAIN          670..894
FT                   /note="Rapamycin-insensitive companion of mTOR middle"
FT                   /evidence="ECO:0000259|SMART:SM01307"
FT   DOMAIN          1076..1148
FT                   /note="Rapamycin-insensitive companion of mTOR"
FT                   /evidence="ECO:0000259|SMART:SM01310"
FT   REGION          1..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          153..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          643..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        153..167
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1291 AA;  143635 MW;  16C17C12924B3588 CRC64;
     MTPTSRAGGP YTGTNTNDAL APPPQRPSQD GRSYSAASIK TAKQGQSYGR SIGVPGSFGA
     ELKSLNSRPD ISRAEFTTYS GADEGDEPTT EQRQADYRDR IDKEMKIKVG TENLLEALNN
     KSAKQARDQR RVVELELNTS NRKIAKLRQD LNAEIQRSKD KGPEQTTSPK RRLSQLFRAA
     PVRSPSYQTQ MQLEGPEVDL DPEVESPTYI LAEKLRALEL EGHPSDYYVG QANDLVELFK
     RHPTLKYDLA WSIFGLRMQM MLLSDSREVV AAGYRVMRYA ITDRKSLQII RALQTDFLVI
     LSLVKESKAR VEREQALKFV RAFLDVKDGA QEIHLAVARI VVAVADHADD QLRGIAILTL
     AEMLLKEPLL VVNSGGLGVL SDAMGSGIYF APETLIEPFL HLMDLPARRG LLKSGFEFSS
     AFASFTEPFS SHSHEDKLRA SARVVSSLFK SWPGLMTLAL HEFLPVRSVV SALYITNTQV
     RTVTLDLLMD ILRITPPSWS SSFIGGRRLT TYGRVTNLRN ETKPSESSWK QSADEKQKRS
     IVQHFTAVAL AVLLRQGLLG GLVHAEGSAP SQALKRRTNL LIAEVLRMTS DMLPQSWSYG
     VQAMPGLFEL ATNFNSEERF QAVATCYQVD SINRTLYRST SGQDNPLKAA EDGSTSRARA
     TSKSQVNAVM DETQFRARMI DTQVLSSVNY TKWDWNLIND LIEGPMVHSK RLQEAMITSK
     FVHRLLGFLR PFKYRFSEAP NTKANQRYVR TACALLRLLL QTQEGARYLE SNKLIPQIGE
     CLAQQDPMSG LTSKTPLFSR ERMSETLVGG YFAMLGTLCS DAKGMQILER WKIINICYHI
     VELKQRDDLI RALLLNLDYT LDSHPRIILS KAMIASSKQM RISATRILRK YAMTPIEQTI
     IGGGAAEWAI KLLVGQLYDP EIEVCEVAIK ILEEACNNIT SLEYVVKCRP ALDHLGEIGA
     PLLLRFLSTS VGYHYLDGLD YITREMDDWF LGRNDTYVTM VEASLARALA DIPDKPPSAL
     DDGLEPQDFG SVPPHFYREL TRTAEGCKLL KAKGHFEEFA ATIQDFAMED EDSETLLKVK
     GCLWAVGNVG SMELGAPFLE SSDVVKYIVQ IAETSKVLTL RGTAFFVLGL VSRSLHGQEI
     LAEYGWDGTV NVMGESLGYV LPLEFNKLFG LGGDSAQNKP SSTIIRSRKG SVSDDDPTSA
     GILASVVKLG NTVLTNKALS ELNGYRNKKA PGFQKPALFR KAMGVMASHA YRIPQYRFVI
     DLFDKSVLRK IVIEDEGSES DALDSAHEDG R
//